Selective blockade of trypanosomatid protein synthesis by a recombinant antibody anti-Trypanosoma cruzi P2β protein.

The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against the C-terminal region of the Trypanosoma cruzi P2β protein (TcP2β) recognizes...

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Autores principales: Maximiliano Juri Ayub, Benson Nyambega, Leandro Simonetti, Tomas Duffy, Silvia A Longhi, Karina A Gómez, Johan Hoebeke, Mariano J Levin, Cristian R Smulski
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/868a09413ac44ebf9c52176ad53a898d
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