Selective blockade of trypanosomatid protein synthesis by a recombinant antibody anti-Trypanosoma cruzi P2β protein.
The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against the C-terminal region of the Trypanosoma cruzi P2β protein (TcP2β) recognizes...
Guardado en:
Autores principales: | Maximiliano Juri Ayub, Benson Nyambega, Leandro Simonetti, Tomas Duffy, Silvia A Longhi, Karina A Gómez, Johan Hoebeke, Mariano J Levin, Cristian R Smulski |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/868a09413ac44ebf9c52176ad53a898d |
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