CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data

CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data

RNA-sequencing is mostly used to assess gene expression; however, it can also give information about genetic variants. Here, the authors present CaSpER, a statistical framework that utilises RNA-sequencing reads to identify and visualise CNV events by integrating transcriptome-wide expression and al...

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Autores principales: Akdes Serin Harmanci, Arif O. Harmanci, Xiaobo Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/868bcf871ac84f19b2bf68709c736e8e
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spelling oai:doaj.org-article:868bcf871ac84f19b2bf68709c736e8e2021-12-02T15:39:25ZCaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data10.1038/s41467-019-13779-x2041-1723https://doaj.org/article/868bcf871ac84f19b2bf68709c736e8e2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13779-xhttps://doaj.org/toc/2041-1723RNA-sequencing is mostly used to assess gene expression; however, it can also give information about genetic variants. Here, the authors present CaSpER, a statistical framework that utilises RNA-sequencing reads to identify and visualise CNV events by integrating transcriptome-wide expression and allelic shift profiles.Akdes Serin HarmanciArif O. HarmanciXiaobo ZhouNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Akdes Serin Harmanci
Arif O. Harmanci
Xiaobo Zhou
CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data
description RNA-sequencing is mostly used to assess gene expression; however, it can also give information about genetic variants. Here, the authors present CaSpER, a statistical framework that utilises RNA-sequencing reads to identify and visualise CNV events by integrating transcriptome-wide expression and allelic shift profiles.
format article
author Akdes Serin Harmanci
Arif O. Harmanci
Xiaobo Zhou
author_facet Akdes Serin Harmanci
Arif O. Harmanci
Xiaobo Zhou
author_sort Akdes Serin Harmanci
title CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data
title_short CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data
title_full CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data
title_fullStr CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data
title_full_unstemmed CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data
title_sort casper identifies and visualizes cnv events by integrative analysis of single-cell or bulk rna-sequencing data
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/868bcf871ac84f19b2bf68709c736e8e
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AT arifoharmanci casperidentifiesandvisualizescnveventsbyintegrativeanalysisofsinglecellorbulkrnasequencingdata
AT xiaobozhou casperidentifiesandvisualizescnveventsbyintegrativeanalysisofsinglecellorbulkrnasequencingdata
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