Development and validation of a weakly supervised deep learning framework to predict the status of molecular pathways and key mutations in colorectal cancer from routine histology images: a retrospective study

Summary: Background: Determining the status of molecular pathways and key mutations in colorectal cancer is crucial for optimal therapeutic decision making. We therefore aimed to develop a novel deep learning pipeline to predict the status of key molecular pathways and mutations from whole-slide im...

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Main Authors: Mohsin Bilal, PhD, Shan E Ahmed Raza, PhD, Ayesha Azam, MBBS, Simon Graham, PhD, Mohammad Ilyas, ProfPhD, Ian A Cree, ProfPhD, David Snead, ProfMBBS, Fayyaz Minhas, PhD, Nasir M Rajpoot, ProfPhD
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/868e1cf7610949dda0fc3e4b9bfb3b3f
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