Comparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study

Arteriovenous fistula (AVF) is the most widely used vascular access by patients undergoing hemodialysis, however, even though the most widely used access to AVF has a high failure rate, and can be affected by problems during its use, among the most common highlights intimal hyperplasia, thrombosis a...

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Autores principales:	J. F. Rangel, W. B. A. Santos, L. H. Pinheiro, T. H. C. Costa, K. L. Bessa, J. P. Ortiz
Formato:	article
Lenguaje:	EN
Publicado:	Isfahan University of Technology 2021
Materias:	arteriovenous fistula; rigid; deformation; pressure variation; flow variation.‎ Mechanical engineering and machinery TJ1-1570
Acceso en línea:	https://doaj.org/article/868eac31425543f1ae8339193bc85427
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spelling	oai:doaj.org-article:868eac31425543f1ae8339193bc854272021-11-13T07:03:04ZComparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study1735-3572https://doaj.org/article/868eac31425543f1ae8339193bc854272021-01-01T00:00:00Zhttp://jafmonline.net/JournalArchive/download?file_ID=56643&issue_ID=1015https://doaj.org/toc/1735-3572Arteriovenous fistula (AVF) is the most widely used vascular access by patients undergoing hemodialysis, however, even though the most widely used access to AVF has a high failure rate, and can be affected by problems during its use, among the most common highlights intimal hyperplasia, thrombosis and stenosis. Studies suggest that recurrent problems in this type of access are directly linked to geometry, flow conditions and stiffness of the vascular wall by the vessels that compose it. The present work seeks to analyze the variation of pressure and flow in rigid and flexible AVF models manufactured from data from an actual patient undergoing treatment. The study was carried out from the acquisition and processing of the patient’s medical examinations (computed tomography), the creation of the geometry, treatment and modeling of said patient, the manufacturing of the AVF models by 3D printing and injection in mold, experimental analysis with pulsatile flow conditions, close to the real physiological conditions, and data analysis. The results obtained show the influence of vascular wall stiffness on flow conditions. In the rigid and flexible model, pressure peaks ranged from 170.98 mmHg to 172.44 mmHg (± 0.02) and 69.83 mmHg to 116.63 mmHg (± 0.03), respectively. The pressure drop between entry and exit in the AVF was also analyzed, presenting a greater value in the flexible model, being approximately three times that of the rigid model. The observed results show the direct relation of the deformation in the flow conditions in the system, and consequently, its direct influence on the pathologies of the vascular system, especially the AVF.J. F. RangelW. B. A. SantosL. H. PinheiroT. H. C. CostaK. L. BessaJ. P. OrtizIsfahan University of Technology articlearteriovenous fistula; rigid; deformation; pressure variation; flow variation.‎Mechanical engineering and machineryTJ1-1570ENJournal of Applied Fluid Mechanics, Vol 14, Iss 6, Pp 1593-1601 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	arteriovenous fistula; rigid; deformation; pressure variation; flow variation.‎ Mechanical engineering and machinery TJ1-1570
spellingShingle	arteriovenous fistula; rigid; deformation; pressure variation; flow variation.‎ Mechanical engineering and machinery TJ1-1570 J. F. Rangel W. B. A. Santos L. H. Pinheiro T. H. C. Costa K. L. Bessa J. P. Ortiz Comparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study
description	Arteriovenous fistula (AVF) is the most widely used vascular access by patients undergoing hemodialysis, however, even though the most widely used access to AVF has a high failure rate, and can be affected by problems during its use, among the most common highlights intimal hyperplasia, thrombosis and stenosis. Studies suggest that recurrent problems in this type of access are directly linked to geometry, flow conditions and stiffness of the vascular wall by the vessels that compose it. The present work seeks to analyze the variation of pressure and flow in rigid and flexible AVF models manufactured from data from an actual patient undergoing treatment. The study was carried out from the acquisition and processing of the patient’s medical examinations (computed tomography), the creation of the geometry, treatment and modeling of said patient, the manufacturing of the AVF models by 3D printing and injection in mold, experimental analysis with pulsatile flow conditions, close to the real physiological conditions, and data analysis. The results obtained show the influence of vascular wall stiffness on flow conditions. In the rigid and flexible model, pressure peaks ranged from 170.98 mmHg to 172.44 mmHg (± 0.02) and 69.83 mmHg to 116.63 mmHg (± 0.03), respectively. The pressure drop between entry and exit in the AVF was also analyzed, presenting a greater value in the flexible model, being approximately three times that of the rigid model. The observed results show the direct relation of the deformation in the flow conditions in the system, and consequently, its direct influence on the pathologies of the vascular system, especially the AVF.
format	article
author	J. F. Rangel W. B. A. Santos L. H. Pinheiro T. H. C. Costa K. L. Bessa J. P. Ortiz
author_facet	J. F. Rangel W. B. A. Santos L. H. Pinheiro T. H. C. Costa K. L. Bessa J. P. Ortiz
author_sort	J. F. Rangel
title	Comparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study
title_short	Comparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study
title_full	Comparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study
title_fullStr	Comparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study
title_full_unstemmed	Comparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study
title_sort	comparison of pulsatile pressure flow through a ‎specific patient's rigid and deformable ‎arteriovenous fistula: in vitro study
publisher	Isfahan University of Technology
publishDate	2021
url	https://doaj.org/article/868eac31425543f1ae8339193bc85427
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Comparison of Pulsatile Pressure Flow through a ‎Specific Patient's Rigid and Deformable ‎Arteriovenous Fistula: In Vitro Study

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