A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei

In eukaryotic cells, kinetochores are large protein complexes that link chromosomes to dynamic microtubule tips, ensuring proper segregation and genomic stability during cell division. Several proteins tightly coordinate kinetochore functions, including the protein kinase aurora kinase B.

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Autores principales:	Manuel Saldivia, Adam J. M. Wollman, Juliana B. T. Carnielli, Nathaniel G. Jones, Mark C. Leake, Christopher Bower-Lepts, Srinivasa P. S. Rao, Jeremy C. Mottram
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/86905287e15d4286a26051507d71d700
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spelling	oai:doaj.org-article:86905287e15d4286a26051507d71d7002021-11-03T21:15:03ZA CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei2150-751110.1128/mBio.00687-21https://doaj.org/article/86905287e15d4286a26051507d71d7002021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00687-21https://doaj.org/toc/2150-7511 In eukaryotic cells, kinetochores are large protein complexes that link chromosomes to dynamic microtubule tips, ensuring proper segregation and genomic stability during cell division. Several proteins tightly coordinate kinetochore functions, including the protein kinase aurora kinase B.Manuel SaldiviaAdam J. M. WollmanJuliana B. T. CarnielliNathaniel G. JonesMark C. LeakeChristopher Bower-LeptsSrinivasa P. S. RaoJeremy C. MottramAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Manuel Saldivia Adam J. M. Wollman Juliana B. T. Carnielli Nathaniel G. Jones Mark C. Leake Christopher Bower-Lepts Srinivasa P. S. Rao Jeremy C. Mottram A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei
description	In eukaryotic cells, kinetochores are large protein complexes that link chromosomes to dynamic microtubule tips, ensuring proper segregation and genomic stability during cell division. Several proteins tightly coordinate kinetochore functions, including the protein kinase aurora kinase B.
format	article
author	Manuel Saldivia Adam J. M. Wollman Juliana B. T. Carnielli Nathaniel G. Jones Mark C. Leake Christopher Bower-Lepts Srinivasa P. S. Rao Jeremy C. Mottram
author_facet	Manuel Saldivia Adam J. M. Wollman Juliana B. T. Carnielli Nathaniel G. Jones Mark C. Leake Christopher Bower-Lepts Srinivasa P. S. Rao Jeremy C. Mottram
author_sort	Manuel Saldivia
title	A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei
title_short	A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei
title_full	A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei
title_fullStr	A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei
title_full_unstemmed	A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei
title_sort	clk1-kkt2 signaling pathway regulating kinetochore assembly in trypanosoma brucei
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/86905287e15d4286a26051507d71d700
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A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei

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