Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

Abstract Formation of blood vessels, or angiogenesis, is crucial to cancer progression. Thus, inhibiting angiogenesis can limit the growth and spread of tumors. The natural polyphenol catechin has moderate anti-tumor activity and interacts with copper, which is essential for angiogenesis. Catechin i...

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Autores principales: Eugene M. H. Yee, Miriam B. Brandl, Eddy Pasquier, Giuseppe Cirillo, Kathleen Kimpton, Maria Kavallaris, Naresh Kumar, Orazio Vittorio
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/86957e54d73e492ebf3c69aaf156aadd
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