Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth

Abstract There is no consistent conclusion on which adiposity measure is best to predict cardiovascular risk factors in youth. The present study aims to assess the performance of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) in predicting abnormal left ventricular...

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Autores principales:	Hong Cheng, Bo Xi, Junting Liu, Yinkun Yan, Jie Mi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8696c343609c495cb3a59d5adc659e26
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spelling	oai:doaj.org-article:8696c343609c495cb3a59d5adc659e262021-11-14T12:24:38ZPerformance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth10.1038/s41598-021-00978-02045-2322https://doaj.org/article/8696c343609c495cb3a59d5adc659e262021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-00978-0https://doaj.org/toc/2045-2322Abstract There is no consistent conclusion on which adiposity measure is best to predict cardiovascular risk factors in youth. The present study aims to assess the performance of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) in predicting abnormal left ventricular structure in Chinese hypertensive youth. A total of 1180 youth aged 6–17 years with hypertension from the China Child and Adolescent Cardiovascular Health Study were included in this study. Logistic regression model, receiver operator characteristic (ROC) curve analysis and net reclassification improvement (NRI) method were used to assess performance of BMI, WC, and WHtR in predicting left ventricular hypertrophy (LVH) and left ventricular geometry (LVG). A 1-standard deviation increment in any of three indexes in predicting LVH and LVG were similar, e.g., with the odds ratios and 95% confidence intervals of 1.34 (1.16–1.55), 1.25 (1.08–1.45) and 1.40 (1.20–1.62), respectively. In addition, ROC analysis and NRI method confirmed the similar performance of three adiposity indexes in predicting LVH and LVG. In conclusion, BMI, WC and WHtR had similar performance in predicting abnormal left ventricular structure in Chinese hypertensive youth, but all three indexes had limited value in prediction. WHtR is a simple and convenient adiposity index for screening youth at high risk of target organ damage.Hong ChengBo XiJunting LiuYinkun YanJie MiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hong Cheng Bo Xi Junting Liu Yinkun Yan Jie Mi Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth
description	Abstract There is no consistent conclusion on which adiposity measure is best to predict cardiovascular risk factors in youth. The present study aims to assess the performance of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) in predicting abnormal left ventricular structure in Chinese hypertensive youth. A total of 1180 youth aged 6–17 years with hypertension from the China Child and Adolescent Cardiovascular Health Study were included in this study. Logistic regression model, receiver operator characteristic (ROC) curve analysis and net reclassification improvement (NRI) method were used to assess performance of BMI, WC, and WHtR in predicting left ventricular hypertrophy (LVH) and left ventricular geometry (LVG). A 1-standard deviation increment in any of three indexes in predicting LVH and LVG were similar, e.g., with the odds ratios and 95% confidence intervals of 1.34 (1.16–1.55), 1.25 (1.08–1.45) and 1.40 (1.20–1.62), respectively. In addition, ROC analysis and NRI method confirmed the similar performance of three adiposity indexes in predicting LVH and LVG. In conclusion, BMI, WC and WHtR had similar performance in predicting abnormal left ventricular structure in Chinese hypertensive youth, but all three indexes had limited value in prediction. WHtR is a simple and convenient adiposity index for screening youth at high risk of target organ damage.
format	article
author	Hong Cheng Bo Xi Junting Liu Yinkun Yan Jie Mi
author_facet	Hong Cheng Bo Xi Junting Liu Yinkun Yan Jie Mi
author_sort	Hong Cheng
title	Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth
title_short	Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth
title_full	Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth
title_fullStr	Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth
title_full_unstemmed	Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth
title_sort	performance of different adiposity measures for predicting left ventricular remodeling in chinese hypertensive youth
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8696c343609c495cb3a59d5adc659e26
work_keys_str_mv	AT hongcheng performanceofdifferentadipositymeasuresforpredictingleftventricularremodelinginchinesehypertensiveyouth AT boxi performanceofdifferentadipositymeasuresforpredictingleftventricularremodelinginchinesehypertensiveyouth AT juntingliu performanceofdifferentadipositymeasuresforpredictingleftventricularremodelinginchinesehypertensiveyouth AT yinkunyan performanceofdifferentadipositymeasuresforpredictingleftventricularremodelinginchinesehypertensiveyouth AT jiemi performanceofdifferentadipositymeasuresforpredictingleftventricularremodelinginchinesehypertensiveyouth
_version_	1718429240990367744

Performance of different adiposity measures for predicting left ventricular remodeling in Chinese hypertensive youth

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