FEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)

The article presents literature data on the lipid peroxidation and antioxidant defense system (LPO-AOD) under normal conditions. Lipid peroxidation is a physiological process which is constantly occurring in cell membranes and has a chain, free-radical mechanism. Free-radical reactions are involved...

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Autor principal: O. A. Gavrilova
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2017
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spelling oai:doaj.org-article:869a974892b1414b8adc0649c48faf192021-11-23T06:14:37ZFEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)2541-94202587-959610.12737/article_59fad50f919f18.64819381https://doaj.org/article/869a974892b1414b8adc0649c48faf192017-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/405https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article presents literature data on the lipid peroxidation and antioxidant defense system (LPO-AOD) under normal conditions. Lipid peroxidation is a physiological process which is constantly occurring in cell membranes and has a chain, free-radical mechanism. Free-radical reactions are involved in the repair of cell membranes, in the processes of phagocytosis and destruction of microorganisms, in conducting nerve impulses, in metabolism of various xenobiotics by liver and in biosynthesis of certain biologically active substances such as prostaglandins. Antioxidant defense neutralizes all kinds of radicals before they cause damage effect in a body. The imbalance in the LPO-AOD system causes oxidative stress. Nowadays research of this process in children of different age is very topical. Thus, reduction of the AOD intensity was proved in case of diseases such as arterial hypertension, chronic gastroduodenitis, influenza, cholelithiasis, pyelonephritis, metabolic syndrome, diabetes mellitus type 1. The conclusion on the necessity of inclusion of drugs with antioxidant action in the complex therapy of various pathological conditions along with the medical methods of treatment is made. Thus, the efficiency of the treatment of various diseases largely depends on the protection of the structure and function of cell membranes, and as a result the inclusion of drugs with antioxidant action in the treatment of almost any pathology in childhood is justified.O. A. GavrilovaScientific Сentre for Family Health and Human Reproduction Problemsarticlelipid peroxidationantioxidant defensechildhood diseasesScienceQRUActa Biomedica Scientifica, Vol 2, Iss 4, Pp 15-22 (2017)
institution DOAJ
collection DOAJ
language RU
topic lipid peroxidation
antioxidant defense
childhood diseases
Science
Q
spellingShingle lipid peroxidation
antioxidant defense
childhood diseases
Science
Q
O. A. Gavrilova
FEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)
description The article presents literature data on the lipid peroxidation and antioxidant defense system (LPO-AOD) under normal conditions. Lipid peroxidation is a physiological process which is constantly occurring in cell membranes and has a chain, free-radical mechanism. Free-radical reactions are involved in the repair of cell membranes, in the processes of phagocytosis and destruction of microorganisms, in conducting nerve impulses, in metabolism of various xenobiotics by liver and in biosynthesis of certain biologically active substances such as prostaglandins. Antioxidant defense neutralizes all kinds of radicals before they cause damage effect in a body. The imbalance in the LPO-AOD system causes oxidative stress. Nowadays research of this process in children of different age is very topical. Thus, reduction of the AOD intensity was proved in case of diseases such as arterial hypertension, chronic gastroduodenitis, influenza, cholelithiasis, pyelonephritis, metabolic syndrome, diabetes mellitus type 1. The conclusion on the necessity of inclusion of drugs with antioxidant action in the complex therapy of various pathological conditions along with the medical methods of treatment is made. Thus, the efficiency of the treatment of various diseases largely depends on the protection of the structure and function of cell membranes, and as a result the inclusion of drugs with antioxidant action in the treatment of almost any pathology in childhood is justified.
format article
author O. A. Gavrilova
author_facet O. A. Gavrilova
author_sort O. A. Gavrilova
title FEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)
title_short FEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)
title_full FEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)
title_fullStr FEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)
title_full_unstemmed FEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)
title_sort features of lipid peroxidation process in normal conditions and in various pathological conditions in children (review of literature)
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2017
url https://doaj.org/article/869a974892b1414b8adc0649c48faf19
work_keys_str_mv AT oagavrilova featuresoflipidperoxidationprocessinnormalconditionsandinvariouspathologicalconditionsinchildrenreviewofliterature
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