Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis

Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis

Objective: Obesity represents a growing health problem that is reaching pandemic dimensions and lacks effective cures, thus highlighting an urgent need for better mechanistic understanding and new therapeutic strategies. Unlike transcription, the function of translation in obesity has hardly been in...

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Main Authors: Nuria Pell, Ester Garcia-Pras, Javier Gallego, Salvador Naranjo-Suarez, Alexandra Balvey, Clara Suñer, Marcos Fernandez-Alfara, Veronica Chanes, Julia Carbo, Marta Ramirez-Pedraza, Oscar Reina, Louise Thingholm, Corinna Bang, Malte Rühlemann, Andre Franke, Robert Schierwagen, Karl P. Rheinwalt, Jonel Trebicka, Raul Mendez, Mercedes Fernandez
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Obesity
Translation
RNA-Binding proteins
Adipose tissue
Microbiome dysbiosis
Internal medicine
RC31-1245
Online Access:https://doaj.org/article/86a68fa47e414fe0a0f7d694e72e9894
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https://doaj.org/article/86a68fa47e414fe0a0f7d694e72e9894

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