A prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK

Abstract A reasonable prediction of infectious diseases’ transmission process under different disease control strategies is an important reference point for policy makers. Here we established a dynamic transmission model via Python and realized comprehensive regulation of disease control measures. W...

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Autores principales: Yuxuan Zhang, Chen Gong, Dawei Li, Zhi-Wei Wang, Shengda D. Pu, Alex W. Robertson, Hong Yu, John Parrington
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/86b1e35bfe8a4649bc8dde3b9e1dcff7
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spelling oai:doaj.org-article:86b1e35bfe8a4649bc8dde3b9e1dcff72021-12-02T18:03:27ZA prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK10.1038/s41598-021-87882-92045-2322https://doaj.org/article/86b1e35bfe8a4649bc8dde3b9e1dcff72021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87882-9https://doaj.org/toc/2045-2322Abstract A reasonable prediction of infectious diseases’ transmission process under different disease control strategies is an important reference point for policy makers. Here we established a dynamic transmission model via Python and realized comprehensive regulation of disease control measures. We classified government interventions into three categories and introduced three parameters as descriptions for the key points in disease control, these being intraregional growth rate, interregional communication rate, and detection rate of infectors. Our simulation predicts the infection by COVID-19 in the UK would be out of control in 73 days without any interventions; at the same time, herd immunity acquisition will begin from the epicentre. After we introduced government interventions, a single intervention is effective in disease control but at huge expense, while combined interventions would be more efficient, among which, enhancing detection number is crucial in the control strategy for COVID-19. In addition, we calculated requirements for the most effective vaccination strategy based on infection numbers in a real situation. Our model was programmed with iterative algorithms, and visualized via cellular automata; it can be applied to similar epidemics in other regions if the basic parameters are inputted, and is able to synthetically mimic the effect of multiple factors in infectious disease control.Yuxuan ZhangChen GongDawei LiZhi-Wei WangShengda D. PuAlex W. RobertsonHong YuJohn ParringtonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Yuxuan Zhang
Chen Gong
Dawei Li
Zhi-Wei Wang
Shengda D. Pu
Alex W. Robertson
Hong Yu
John Parrington
A prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK
description Abstract A reasonable prediction of infectious diseases’ transmission process under different disease control strategies is an important reference point for policy makers. Here we established a dynamic transmission model via Python and realized comprehensive regulation of disease control measures. We classified government interventions into three categories and introduced three parameters as descriptions for the key points in disease control, these being intraregional growth rate, interregional communication rate, and detection rate of infectors. Our simulation predicts the infection by COVID-19 in the UK would be out of control in 73 days without any interventions; at the same time, herd immunity acquisition will begin from the epicentre. After we introduced government interventions, a single intervention is effective in disease control but at huge expense, while combined interventions would be more efficient, among which, enhancing detection number is crucial in the control strategy for COVID-19. In addition, we calculated requirements for the most effective vaccination strategy based on infection numbers in a real situation. Our model was programmed with iterative algorithms, and visualized via cellular automata; it can be applied to similar epidemics in other regions if the basic parameters are inputted, and is able to synthetically mimic the effect of multiple factors in infectious disease control.
format article
author Yuxuan Zhang
Chen Gong
Dawei Li
Zhi-Wei Wang
Shengda D. Pu
Alex W. Robertson
Hong Yu
John Parrington
author_facet Yuxuan Zhang
Chen Gong
Dawei Li
Zhi-Wei Wang
Shengda D. Pu
Alex W. Robertson
Hong Yu
John Parrington
author_sort Yuxuan Zhang
title A prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK
title_short A prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK
title_full A prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK
title_fullStr A prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK
title_full_unstemmed A prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of COVID-19 in the UK
title_sort prognostic dynamic model applicable to infectious diseases providing easily visualized guides: a case study of covid-19 in the uk
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/86b1e35bfe8a4649bc8dde3b9e1dcff7
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