Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus

Glycans are abundant biomolecules that mediate essential biological processes, but their chemical synthesis is challenging. Here, the authors report the synthesis of glycans up to a 128-mer, which represents the O-antigen of Bacteroides vulgatus lipopolysaccharide and one of the longest synthetic gl...

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Autores principales:	Qian Zhu, Zhengnan Shen, Fabrizio Chiodo, Simone Nicolardi, Antonio Molinaro, Alba Silipo, Biao Yu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/86bc33511a5442518db1317c3d762cbc
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spelling	oai:doaj.org-article:86bc33511a5442518db1317c3d762cbc2021-12-02T15:10:40ZChemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus10.1038/s41467-020-17992-x2041-1723https://doaj.org/article/86bc33511a5442518db1317c3d762cbc2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17992-xhttps://doaj.org/toc/2041-1723Glycans are abundant biomolecules that mediate essential biological processes, but their chemical synthesis is challenging. Here, the authors report the synthesis of glycans up to a 128-mer, which represents the O-antigen of Bacteroides vulgatus lipopolysaccharide and one of the longest synthetic glycans to date.Qian ZhuZhengnan ShenFabrizio ChiodoSimone NicolardiAntonio MolinaroAlba SilipoBiao YuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qian Zhu Zhengnan Shen Fabrizio Chiodo Simone Nicolardi Antonio Molinaro Alba Silipo Biao Yu Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus
description	Glycans are abundant biomolecules that mediate essential biological processes, but their chemical synthesis is challenging. Here, the authors report the synthesis of glycans up to a 128-mer, which represents the O-antigen of Bacteroides vulgatus lipopolysaccharide and one of the longest synthetic glycans to date.
format	article
author	Qian Zhu Zhengnan Shen Fabrizio Chiodo Simone Nicolardi Antonio Molinaro Alba Silipo Biao Yu
author_facet	Qian Zhu Zhengnan Shen Fabrizio Chiodo Simone Nicolardi Antonio Molinaro Alba Silipo Biao Yu
author_sort	Qian Zhu
title	Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus
title_short	Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus
title_full	Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus
title_fullStr	Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus
title_full_unstemmed	Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus
title_sort	chemical synthesis of glycans up to a 128-mer relevant to the o-antigen of bacteroides vulgatus
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/86bc33511a5442518db1317c3d762cbc
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Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus

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