A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia

A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia

Pigmentation variation in humans is influenced by complex genetic architecture in different populations. Here, the authors perform a genome-wide association analysis involving > 6,000 Latin Americans for pigmentation of skin and eyes, and identify known and novel genetic associations.

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Autores principales: Kaustubh Adhikari, Javier Mendoza-Revilla, Anood Sohail, Macarena Fuentes-Guajardo, Jodie Lampert, Juan Camilo Chacón-Duque, Malena Hurtado, Valeria Villegas, Vanessa Granja, Victor Acuña-Alonzo, Claudia Jaramillo, William Arias, Rodrigo Barquera Lozano, Paola Everardo, Jorge Gómez-Valdés, Hugo Villamil-Ramírez, Caio C. Silva de Cerqueira, Tábita Hunemeier, Virginia Ramallo, Lavinia Schuler-Faccini, Francisco M. Salzano, Rolando Gonzalez-José, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Carla Gallo, Giovanni Poletti, Gabriel Bedoya, Francisco Rothhammer, Desmond J. Tobin, Matteo Fumagalli, David Balding, Andrés Ruiz-Linares
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/86c730a9ce5e412d8c65dc5984f7c306
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spelling oai:doaj.org-article:86c730a9ce5e412d8c65dc5984f7c3062021-12-02T15:36:22ZA GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia10.1038/s41467-018-08147-02041-1723https://doaj.org/article/86c730a9ce5e412d8c65dc5984f7c3062019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08147-0https://doaj.org/toc/2041-1723Pigmentation variation in humans is influenced by complex genetic architecture in different populations. Here, the authors perform a genome-wide association analysis involving > 6,000 Latin Americans for pigmentation of skin and eyes, and identify known and novel genetic associations.Kaustubh AdhikariJavier Mendoza-RevillaAnood SohailMacarena Fuentes-GuajardoJodie LampertJuan Camilo Chacón-DuqueMalena HurtadoValeria VillegasVanessa GranjaVictor Acuña-AlonzoClaudia JaramilloWilliam AriasRodrigo Barquera LozanoPaola EverardoJorge Gómez-ValdésHugo Villamil-RamírezCaio C. Silva de CerqueiraTábita HunemeierVirginia RamalloLavinia Schuler-FacciniFrancisco M. SalzanoRolando Gonzalez-JoséMaria-Cátira BortoliniSamuel Canizales-QuinterosCarla GalloGiovanni PolettiGabriel BedoyaFrancisco RothhammerDesmond J. TobinMatteo FumagalliDavid BaldingAndrés Ruiz-LinaresNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kaustubh Adhikari
Javier Mendoza-Revilla
Anood Sohail
Macarena Fuentes-Guajardo
Jodie Lampert
Juan Camilo Chacón-Duque
Malena Hurtado
Valeria Villegas
Vanessa Granja
Victor Acuña-Alonzo
Claudia Jaramillo
William Arias
Rodrigo Barquera Lozano
Paola Everardo
Jorge Gómez-Valdés
Hugo Villamil-Ramírez
Caio C. Silva de Cerqueira
Tábita Hunemeier
Virginia Ramallo
Lavinia Schuler-Faccini
Francisco M. Salzano
Rolando Gonzalez-José
Maria-Cátira Bortolini
Samuel Canizales-Quinteros
Carla Gallo
Giovanni Poletti
Gabriel Bedoya
Francisco Rothhammer
Desmond J. Tobin
Matteo Fumagalli
David Balding
Andrés Ruiz-Linares
A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
description Pigmentation variation in humans is influenced by complex genetic architecture in different populations. Here, the authors perform a genome-wide association analysis involving > 6,000 Latin Americans for pigmentation of skin and eyes, and identify known and novel genetic associations.
format article
author Kaustubh Adhikari
Javier Mendoza-Revilla
Anood Sohail
Macarena Fuentes-Guajardo
Jodie Lampert
Juan Camilo Chacón-Duque
Malena Hurtado
Valeria Villegas
Vanessa Granja
Victor Acuña-Alonzo
Claudia Jaramillo
William Arias
Rodrigo Barquera Lozano
Paola Everardo
Jorge Gómez-Valdés
Hugo Villamil-Ramírez
Caio C. Silva de Cerqueira
Tábita Hunemeier
Virginia Ramallo
Lavinia Schuler-Faccini
Francisco M. Salzano
Rolando Gonzalez-José
Maria-Cátira Bortolini
Samuel Canizales-Quinteros
Carla Gallo
Giovanni Poletti
Gabriel Bedoya
Francisco Rothhammer
Desmond J. Tobin
Matteo Fumagalli
David Balding
Andrés Ruiz-Linares
author_facet Kaustubh Adhikari
Javier Mendoza-Revilla
Anood Sohail
Macarena Fuentes-Guajardo
Jodie Lampert
Juan Camilo Chacón-Duque
Malena Hurtado
Valeria Villegas
Vanessa Granja
Victor Acuña-Alonzo
Claudia Jaramillo
William Arias
Rodrigo Barquera Lozano
Paola Everardo
Jorge Gómez-Valdés
Hugo Villamil-Ramírez
Caio C. Silva de Cerqueira
Tábita Hunemeier
Virginia Ramallo
Lavinia Schuler-Faccini
Francisco M. Salzano
Rolando Gonzalez-José
Maria-Cátira Bortolini
Samuel Canizales-Quinteros
Carla Gallo
Giovanni Poletti
Gabriel Bedoya
Francisco Rothhammer
Desmond J. Tobin
Matteo Fumagalli
David Balding
Andrés Ruiz-Linares
author_sort Kaustubh Adhikari
title A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
title_short A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
title_full A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
title_fullStr A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
title_full_unstemmed A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia
title_sort gwas in latin americans highlights the convergent evolution of lighter skin pigmentation in eurasia
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/86c730a9ce5e412d8c65dc5984f7c306
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