The <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Mismatch Repair <italic toggle="yes">MSH2</italic> Homolog Is Important for Virulence and Azole Resistance

The <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Mismatch Repair <italic toggle="yes">MSH2</italic> Homolog Is Important for Virulence and Azole Resistance

ABSTRACT The genetic stability of every living organism depends on accurate DNA replication and repair systems. Here, we investigated the Aspergillus fumigatus MSH2 mismatch repair (MMR) gene MshA and how it impacts virulence and the evolution of azole resistance. We examined mshA gene variation in...

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Autores principales: Thaila Fernanda dos Reis, Lilian Pereira Silva, Patrícia Alves de Castro, Rafaela Andrade do Carmo, Marjorie Mendes Marini, José Franco da Silveira, Beatriz Henriques Ferreira, Fernando Rodrigues, Abigail Lee Lind, Antonis Rokas, Gustavo H. Goldman
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Aspergillus fumigatus
DNA repair
MSH2
azole resistance
virulence
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/86d83744d786492d92b5986ec03a402b
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