A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent

Robert Murray,1 Joseph T Tobias1– 3 1Department of Pediatrics, Division of Pediatric Critical Care Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 2Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 3Department of Anesthesiology & Pa...

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Autores principales:	Murray R, Tobias JT
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	enoxaparin thrombocytosis platelet count heparin anticoagulation Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/86d8dc236440452a8d2c395a8746fd30
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spelling	oai:doaj.org-article:86d8dc236440452a8d2c395a8746fd302021-12-02T17:13:58ZA Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent1179-1438https://doaj.org/article/86d8dc236440452a8d2c395a8746fd302021-10-01T00:00:00Zhttps://www.dovepress.com/a-case-of-thrombocytosis-associated-with-enoxaparin-therapy-in-an-adol-peer-reviewed-fulltext-article-CPAAhttps://doaj.org/toc/1179-1438Robert Murray,1 Joseph T Tobias1– 3 1Department of Pediatrics, Division of Pediatric Critical Care Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 2Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 3Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USACorrespondence: Robert MurrayDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, Nationwide Children’s Hospital, 700 Children’s Drive, Columbus, OH, 43205, USATel +1 614 722-4200Fax +1 614 722-4203Email Robert.Murray@Nationwidechildrens.orgAbstract: Secondary thrombocytosis, often referred to as a reactive thrombocytosis, is more common than primary thrombocytosis and has many potential etiologies including anemia, infection, inflammation, medications, and post-splenectomy. When considering the critically ill patient in the ICU setting potential medication-related etiologies of thrombocytosis should be included in the differential diagnosis. We present a 15-year-old adolescent with a traumatic brain injury who developed thrombocytosis that was temporally related to the administration of enoxaparin. There was a prompt return of the platelet count to normal following the discontinuation of enoxaparin therapy which led to the probable diagnosis of enoxaparin-induced thrombocytosis.Keywords: enoxaparin, thrombocytosis, platelet count, heparin, anticoagulationMurray RTobias JTDove Medical Pressarticleenoxaparinthrombocytosisplatelet countheparinanticoagulationTherapeutics. PharmacologyRM1-950ENClinical Pharmacology: Advances and Applications, Vol Volume 13, Pp 203-207 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	enoxaparin thrombocytosis platelet count heparin anticoagulation Therapeutics. Pharmacology RM1-950
spellingShingle	enoxaparin thrombocytosis platelet count heparin anticoagulation Therapeutics. Pharmacology RM1-950 Murray R Tobias JT A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent
description	Robert Murray,1 Joseph T Tobias1– 3 1Department of Pediatrics, Division of Pediatric Critical Care Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 2Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 3Department of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USACorrespondence: Robert MurrayDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, Nationwide Children’s Hospital, 700 Children’s Drive, Columbus, OH, 43205, USATel +1 614 722-4200Fax +1 614 722-4203Email Robert.Murray@Nationwidechildrens.orgAbstract: Secondary thrombocytosis, often referred to as a reactive thrombocytosis, is more common than primary thrombocytosis and has many potential etiologies including anemia, infection, inflammation, medications, and post-splenectomy. When considering the critically ill patient in the ICU setting potential medication-related etiologies of thrombocytosis should be included in the differential diagnosis. We present a 15-year-old adolescent with a traumatic brain injury who developed thrombocytosis that was temporally related to the administration of enoxaparin. There was a prompt return of the platelet count to normal following the discontinuation of enoxaparin therapy which led to the probable diagnosis of enoxaparin-induced thrombocytosis.Keywords: enoxaparin, thrombocytosis, platelet count, heparin, anticoagulation
format	article
author	Murray R Tobias JT
author_facet	Murray R Tobias JT
author_sort	Murray R
title	A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent
title_short	A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent
title_full	A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent
title_fullStr	A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent
title_full_unstemmed	A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent
title_sort	case of thrombocytosis associated with enoxaparin therapy in an adolescent
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/86d8dc236440452a8d2c395a8746fd30
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A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent

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