Discriminative Dictionary Learning for Autism Spectrum Disorder Identification

Autism Spectrum Disorder (ASD) is a group of lifelong neurodevelopmental disorders with complicated causes. A key symptom of ASD patients is their impaired interpersonal communication ability. Recent study shows that face scanning patterns of individuals with ASD are often different from those of ty...

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Autores principales: Wenbo Liu, Ming Li, Xiaobing Zou, Bhiksha Raj
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/86e2af5b4a82450ba20cc9a70eca4628
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spelling oai:doaj.org-article:86e2af5b4a82450ba20cc9a70eca46282021-11-08T06:11:30ZDiscriminative Dictionary Learning for Autism Spectrum Disorder Identification1662-518810.3389/fncom.2021.662401https://doaj.org/article/86e2af5b4a82450ba20cc9a70eca46282021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fncom.2021.662401/fullhttps://doaj.org/toc/1662-5188Autism Spectrum Disorder (ASD) is a group of lifelong neurodevelopmental disorders with complicated causes. A key symptom of ASD patients is their impaired interpersonal communication ability. Recent study shows that face scanning patterns of individuals with ASD are often different from those of typical developing (TD) ones. Such abnormality motivates us to study the feasibility of identifying ASD children based on their face scanning patterns with machine learning methods. In this paper, we consider using the bag-of-words (BoW) model to encode the face scanning patterns, and propose a novel dictionary learning method based on dual mode seeking for better BoW representation. Unlike k-means which is broadly used in conventional BoW models to learn dictionaries, the proposed method captures discriminative information by finding atoms which maximizes both the purity and coverage of belonging samples within one class. Compared to the rich literature of ASD studies from psychology and neural science, our work marks one of the relatively few attempts to directly identify high-functioning ASD children with machine learning methods. Experiments demonstrate the superior performance of our method with considerable gain over several baselines. Although the proposed work is yet too preliminary to directly replace existing autism diagnostic observation schedules in the clinical practice, it shed light on future applications of machine learning methods in early screening of ASD.Wenbo LiuWenbo LiuMing LiMing LiXiaobing ZouBhiksha RajBhiksha RajFrontiers Media S.A.articlediscriminative dictionary learningautism spectrum disordermode seekingmachine learningeye gazeNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENFrontiers in Computational Neuroscience, Vol 15 (2021)
institution DOAJ
collection DOAJ
language EN
topic discriminative dictionary learning
autism spectrum disorder
mode seeking
machine learning
eye gaze
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
spellingShingle discriminative dictionary learning
autism spectrum disorder
mode seeking
machine learning
eye gaze
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Wenbo Liu
Wenbo Liu
Ming Li
Ming Li
Xiaobing Zou
Bhiksha Raj
Bhiksha Raj
Discriminative Dictionary Learning for Autism Spectrum Disorder Identification
description Autism Spectrum Disorder (ASD) is a group of lifelong neurodevelopmental disorders with complicated causes. A key symptom of ASD patients is their impaired interpersonal communication ability. Recent study shows that face scanning patterns of individuals with ASD are often different from those of typical developing (TD) ones. Such abnormality motivates us to study the feasibility of identifying ASD children based on their face scanning patterns with machine learning methods. In this paper, we consider using the bag-of-words (BoW) model to encode the face scanning patterns, and propose a novel dictionary learning method based on dual mode seeking for better BoW representation. Unlike k-means which is broadly used in conventional BoW models to learn dictionaries, the proposed method captures discriminative information by finding atoms which maximizes both the purity and coverage of belonging samples within one class. Compared to the rich literature of ASD studies from psychology and neural science, our work marks one of the relatively few attempts to directly identify high-functioning ASD children with machine learning methods. Experiments demonstrate the superior performance of our method with considerable gain over several baselines. Although the proposed work is yet too preliminary to directly replace existing autism diagnostic observation schedules in the clinical practice, it shed light on future applications of machine learning methods in early screening of ASD.
format article
author Wenbo Liu
Wenbo Liu
Ming Li
Ming Li
Xiaobing Zou
Bhiksha Raj
Bhiksha Raj
author_facet Wenbo Liu
Wenbo Liu
Ming Li
Ming Li
Xiaobing Zou
Bhiksha Raj
Bhiksha Raj
author_sort Wenbo Liu
title Discriminative Dictionary Learning for Autism Spectrum Disorder Identification
title_short Discriminative Dictionary Learning for Autism Spectrum Disorder Identification
title_full Discriminative Dictionary Learning for Autism Spectrum Disorder Identification
title_fullStr Discriminative Dictionary Learning for Autism Spectrum Disorder Identification
title_full_unstemmed Discriminative Dictionary Learning for Autism Spectrum Disorder Identification
title_sort discriminative dictionary learning for autism spectrum disorder identification
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/86e2af5b4a82450ba20cc9a70eca4628
work_keys_str_mv AT wenboliu discriminativedictionarylearningforautismspectrumdisorderidentification
AT wenboliu discriminativedictionarylearningforautismspectrumdisorderidentification
AT mingli discriminativedictionarylearningforautismspectrumdisorderidentification
AT mingli discriminativedictionarylearningforautismspectrumdisorderidentification
AT xiaobingzou discriminativedictionarylearningforautismspectrumdisorderidentification
AT bhiksharaj discriminativedictionarylearningforautismspectrumdisorderidentification
AT bhiksharaj discriminativedictionarylearningforautismspectrumdisorderidentification
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