The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells
The molecular organization of exocytic vesicles regulates their transport and fusion. Prasai, Taraska, and colleagues use correlative light and electron microscopy, along with 3D tomography and gold labeling, to directly map proteins on single exocytic organelles at the plasma membrane.
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Nature Portfolio
2021
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oai:doaj.org-article:86e32c39b312499b9dcc591ff2ac06532021-12-02T18:02:51ZThe nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells10.1038/s41467-021-24167-92041-1723https://doaj.org/article/86e32c39b312499b9dcc591ff2ac06532021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24167-9https://doaj.org/toc/2041-1723The molecular organization of exocytic vesicles regulates their transport and fusion. Prasai, Taraska, and colleagues use correlative light and electron microscopy, along with 3D tomography and gold labeling, to directly map proteins on single exocytic organelles at the plasma membrane.Bijeta PrasaiGideon J. HaberMarie-Paule StrubRegina AhnJohn A. CiemnieckiKem A. SochackiJustin W. TaraskaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Bijeta Prasai Gideon J. Haber Marie-Paule Strub Regina Ahn John A. Ciemniecki Kem A. Sochacki Justin W. Taraska The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells |
| description |
The molecular organization of exocytic vesicles regulates their transport and fusion. Prasai, Taraska, and colleagues use correlative light and electron microscopy, along with 3D tomography and gold labeling, to directly map proteins on single exocytic organelles at the plasma membrane. |
| format |
article |
| author |
Bijeta Prasai Gideon J. Haber Marie-Paule Strub Regina Ahn John A. Ciemniecki Kem A. Sochacki Justin W. Taraska |
| author_facet |
Bijeta Prasai Gideon J. Haber Marie-Paule Strub Regina Ahn John A. Ciemniecki Kem A. Sochacki Justin W. Taraska |
| author_sort |
Bijeta Prasai |
| title |
The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells |
| title_short |
The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells |
| title_full |
The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells |
| title_fullStr |
The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells |
| title_full_unstemmed |
The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells |
| title_sort |
nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/86e32c39b312499b9dcc591ff2ac0653 |
| work_keys_str_mv |
AT bijetaprasai thenanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT gideonjhaber thenanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT mariepaulestrub thenanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT reginaahn thenanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT johnaciemniecki thenanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT kemasochacki thenanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT justinwtaraska thenanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT bijetaprasai nanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT gideonjhaber nanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT mariepaulestrub nanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT reginaahn nanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT johnaciemniecki nanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT kemasochacki nanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells AT justinwtaraska nanoscalemolecularmorphologyofdockedexocyticdensecorevesiclesinneuroendocrinecells |
| _version_ |
1718378878320246784 |