Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening

Abstract We evaluated the reliability and accuracy of the noncontact CT-1P tonopachymeter (Topcon, Japan) in terms of intraocular pressure (IOP) and central corneal thickness (CCT). One hundred sixty-three healthy participants and 33 patients with open angle glaucoma were enrolled. IOPs were measure...

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Autores principales:	Jinho Lee, Hyuk Jin Choi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/86e52c1c8fd44232beb2701f304902bd
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spelling	oai:doaj.org-article:86e52c1c8fd44232beb2701f304902bd2021-12-02T17:20:11ZAccuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening10.1038/s41598-021-88364-82045-2322https://doaj.org/article/86e52c1c8fd44232beb2701f304902bd2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88364-8https://doaj.org/toc/2045-2322Abstract We evaluated the reliability and accuracy of the noncontact CT-1P tonopachymeter (Topcon, Japan) in terms of intraocular pressure (IOP) and central corneal thickness (CCT). One hundred sixty-three healthy participants and 33 patients with open angle glaucoma were enrolled. IOPs were measured by CT-1P (T-IOP) and Goldmann applanation tonometer (G-IOP), and CCTs were measured by the CT-1P (T-CCT) and an ultrasound pachymeter (US-CCT). Both CCT instrument-adjusted (T-IOP-C) and unadjusted T-IOPs (T-IOP-NC) were included. Pearson correlation coefficients and biases assessed with Bland–Altman analysis with 95% confidence interval (CI) were calculated for reliability evaluation. Intrasession repeatability was excellent for both T-IOP (intraclass correlation coefficient [ICC] 0.91) and T-CCT (ICC 0.98). Intersession reproducibility was also excellent for T-CCT (ICC 0.94). T-IOP-NC and T-IOP-C both showed significant correlations with G-IOP (r = 0.801, P < 0.001 and r = 0.658, P < 0.001, respectively). T-CCT was also strongly correlated with US-CCT (r = 0.958; P < 0.001). T-IOP-NC and T-IOP-C both showed a positive bias (1.37 mmHg, 95% CI [1.14, 1.61] and 2.77 mmHg, 95% CI [2.49, 3.05], respectively). T-CCT showed a negative bias of − 17.3 µm (95% CI [−18.8, − 15.8]). With cautious interpretation, the CT-1P may offer good feasibility for IOP and CCT measurement in screening centers.Jinho LeeHyuk Jin ChoiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jinho Lee Hyuk Jin Choi Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening
description	Abstract We evaluated the reliability and accuracy of the noncontact CT-1P tonopachymeter (Topcon, Japan) in terms of intraocular pressure (IOP) and central corneal thickness (CCT). One hundred sixty-three healthy participants and 33 patients with open angle glaucoma were enrolled. IOPs were measured by CT-1P (T-IOP) and Goldmann applanation tonometer (G-IOP), and CCTs were measured by the CT-1P (T-CCT) and an ultrasound pachymeter (US-CCT). Both CCT instrument-adjusted (T-IOP-C) and unadjusted T-IOPs (T-IOP-NC) were included. Pearson correlation coefficients and biases assessed with Bland–Altman analysis with 95% confidence interval (CI) were calculated for reliability evaluation. Intrasession repeatability was excellent for both T-IOP (intraclass correlation coefficient [ICC] 0.91) and T-CCT (ICC 0.98). Intersession reproducibility was also excellent for T-CCT (ICC 0.94). T-IOP-NC and T-IOP-C both showed significant correlations with G-IOP (r = 0.801, P < 0.001 and r = 0.658, P < 0.001, respectively). T-CCT was also strongly correlated with US-CCT (r = 0.958; P < 0.001). T-IOP-NC and T-IOP-C both showed a positive bias (1.37 mmHg, 95% CI [1.14, 1.61] and 2.77 mmHg, 95% CI [2.49, 3.05], respectively). T-CCT showed a negative bias of − 17.3 µm (95% CI [−18.8, − 15.8]). With cautious interpretation, the CT-1P may offer good feasibility for IOP and CCT measurement in screening centers.
format	article
author	Jinho Lee Hyuk Jin Choi
author_facet	Jinho Lee Hyuk Jin Choi
author_sort	Jinho Lee
title	Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening
title_short	Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening
title_full	Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening
title_fullStr	Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening
title_full_unstemmed	Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening
title_sort	accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/86e52c1c8fd44232beb2701f304902bd
work_keys_str_mv	AT jinholee accuracyandreliabilityofmeasurementsobtainedwithanoncontacttonopachymeterforclinicaluseinmassscreening AT hyukjinchoi accuracyandreliabilityofmeasurementsobtainedwithanoncontacttonopachymeterforclinicaluseinmassscreening
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Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening

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