PCDH18 is frequently inactivated by promoter methylation in colorectal cancer

PCDH18 is frequently inactivated by promoter methylation in colorectal cancer

Abstract Protocadherin18 (PCDH18) was found to be preferentially methylated and inactivated in colorectal cancer (CRC) using bioinformatics tools. However, its biologic role in tumorgenesis remains unclear. Herein, we aimed to elucidate its epigenetic regulation and biological functions in CRC. The...

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Autores principales: Dan Zhou, Weiwei Tang, Guoqiang Su, Mingquan Cai, Han-Xiang An, Yun Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/86ea3e61d1f44fe1b263cc2f241253d6
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