Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children

Seasonal malaria chemoprevention provides substantial benefit for young children, but resistance to used drugs will likely develop. Here, Chotsiri et al. evaluate the use of dihydroartemisinin-piperaquine as a regimen in 179 children, and population-based simulations suggest that small children woul...

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Autores principales:	Palang Chotsiri, Issaka Zongo, Paul Milligan, Yves Daniel Compaore, Anyirékun Fabrice Somé, Daniel Chandramohan, Warunee Hanpithakpong, François Nosten, Brian Greenwood, Philip J. Rosenthal, Nicholas J. White, Jean-Bosco Ouédraogo, Joel Tarning
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/86ec31b424e24336afbb7777111820e8
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spelling	oai:doaj.org-article:86ec31b424e24336afbb7777111820e82021-12-02T15:36:01ZOptimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children10.1038/s41467-019-08297-92041-1723https://doaj.org/article/86ec31b424e24336afbb7777111820e82019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08297-9https://doaj.org/toc/2041-1723Seasonal malaria chemoprevention provides substantial benefit for young children, but resistance to used drugs will likely develop. Here, Chotsiri et al. evaluate the use of dihydroartemisinin-piperaquine as a regimen in 179 children, and population-based simulations suggest that small children would benefit from a higher and extended dosage.Palang ChotsiriIssaka ZongoPaul MilliganYves Daniel CompaoreAnyirékun Fabrice SoméDaniel ChandramohanWarunee HanpithakpongFrançois NostenBrian GreenwoodPhilip J. RosenthalNicholas J. WhiteJean-Bosco OuédraogoJoel TarningNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Palang Chotsiri Issaka Zongo Paul Milligan Yves Daniel Compaore Anyirékun Fabrice Somé Daniel Chandramohan Warunee Hanpithakpong François Nosten Brian Greenwood Philip J. Rosenthal Nicholas J. White Jean-Bosco Ouédraogo Joel Tarning Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
description	Seasonal malaria chemoprevention provides substantial benefit for young children, but resistance to used drugs will likely develop. Here, Chotsiri et al. evaluate the use of dihydroartemisinin-piperaquine as a regimen in 179 children, and population-based simulations suggest that small children would benefit from a higher and extended dosage.
format	article
author	Palang Chotsiri Issaka Zongo Paul Milligan Yves Daniel Compaore Anyirékun Fabrice Somé Daniel Chandramohan Warunee Hanpithakpong François Nosten Brian Greenwood Philip J. Rosenthal Nicholas J. White Jean-Bosco Ouédraogo Joel Tarning
author_facet	Palang Chotsiri Issaka Zongo Paul Milligan Yves Daniel Compaore Anyirékun Fabrice Somé Daniel Chandramohan Warunee Hanpithakpong François Nosten Brian Greenwood Philip J. Rosenthal Nicholas J. White Jean-Bosco Ouédraogo Joel Tarning
author_sort	Palang Chotsiri
title	Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
title_short	Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
title_full	Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
title_fullStr	Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
title_full_unstemmed	Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
title_sort	optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/86ec31b424e24336afbb7777111820e8
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Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children

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