Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report
Background/Aims To evaluate temporal trends of atrial fibrillation (AF) prevalence in critically ill patients who received prolonged mechanical ventilation (MV) in the United States. Methods We used the 2008 to 2014 National Inpatient Sample to compute the weighted prevalence of AF among hospitalize...
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The Korean Association of Internal Medicine
2021
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oai:doaj.org-article:86f69258d89540dd945fcfa820725d392021-11-08T00:59:06ZAtrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report1226-33032005-664810.3904/kjim.2020.142https://doaj.org/article/86f69258d89540dd945fcfa820725d392021-11-01T00:00:00Zhttp://www.kjim.org/upload/pdf/kjim-2020-142.pdfhttps://doaj.org/toc/1226-3303https://doaj.org/toc/2005-6648Background/Aims To evaluate temporal trends of atrial fibrillation (AF) prevalence in critically ill patients who received prolonged mechanical ventilation (MV) in the United States. Methods We used the 2008 to 2014 National Inpatient Sample to compute the weighted prevalence of AF among hospitalized adult patients on prolonged MV. We used multivariable-adjusted models to evaluate the association of AF with clinical factors, in-hospital mortality, hospitalization cost, and length of stay (LOS). Results We identified 2,578,165 patients who received prolonged MV (21.27% of AF patients). The prevalence of AF increased from 14.63% in 2008 to 24.43% in 2014 (p for trend < 0.0001). Amongst different phenotypes of critically ill patients, the prevalence of AF increased in patients with severe sepsis, asthma exacerbation, congestive heart failure exacerbation, acute stroke, and cardiac arrest. Older age, male sex, white race, medicare access, higher income, urban teaching hospital setting, and Western region were associated with a higher prevalence of AF. AF in critical illness was a risk factor for in-hospital death (odds ratio, 1.13; 95% confidence interval, 1.11 to 1.15), but in-hospital mortality in critically ill patients with AF decreased from 11.6% to 8.3%. AF was linked to prolonged LOS (2%, p < 0.0001) and high hospitalization cost (4%, p < 0.0001). LOS (−1%, p < 0.0001) and hospitalization cost (−4%, p < 0.0001) decreased yearly. Conclusions The prevalence of comorbid AF is increasing, particularly in older patients. AF may lead to poorer prognosis, and high-quality intensive care is imperative for this population.Zhen LinHedong HanWei GuoXin WeiZhijian GuoShujie ZhaiShuai LiYiming RuanFangyuan HuDongdong LiJia HeThe Korean Association of Internal Medicinearticlerespirationartificialcritical illnessatrial fibrillationprevalenceoutcomeMedicineRENThe Korean Journal of Internal Medicine, Vol 36, Iss 6, Pp 1389-1401 (2021) |
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DOAJ |
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respiration artificial critical illness atrial fibrillation prevalence outcome Medicine R |
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respiration artificial critical illness atrial fibrillation prevalence outcome Medicine R Zhen Lin Hedong Han Wei Guo Xin Wei Zhijian Guo Shujie Zhai Shuai Li Yiming Ruan Fangyuan Hu Dongdong Li Jia He Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report |
| description |
Background/Aims To evaluate temporal trends of atrial fibrillation (AF) prevalence in critically ill patients who received prolonged mechanical ventilation (MV) in the United States. Methods We used the 2008 to 2014 National Inpatient Sample to compute the weighted prevalence of AF among hospitalized adult patients on prolonged MV. We used multivariable-adjusted models to evaluate the association of AF with clinical factors, in-hospital mortality, hospitalization cost, and length of stay (LOS). Results We identified 2,578,165 patients who received prolonged MV (21.27% of AF patients). The prevalence of AF increased from 14.63% in 2008 to 24.43% in 2014 (p for trend < 0.0001). Amongst different phenotypes of critically ill patients, the prevalence of AF increased in patients with severe sepsis, asthma exacerbation, congestive heart failure exacerbation, acute stroke, and cardiac arrest. Older age, male sex, white race, medicare access, higher income, urban teaching hospital setting, and Western region were associated with a higher prevalence of AF. AF in critical illness was a risk factor for in-hospital death (odds ratio, 1.13; 95% confidence interval, 1.11 to 1.15), but in-hospital mortality in critically ill patients with AF decreased from 11.6% to 8.3%. AF was linked to prolonged LOS (2%, p < 0.0001) and high hospitalization cost (4%, p < 0.0001). LOS (−1%, p < 0.0001) and hospitalization cost (−4%, p < 0.0001) decreased yearly. Conclusions The prevalence of comorbid AF is increasing, particularly in older patients. AF may lead to poorer prognosis, and high-quality intensive care is imperative for this population. |
| format |
article |
| author |
Zhen Lin Hedong Han Wei Guo Xin Wei Zhijian Guo Shujie Zhai Shuai Li Yiming Ruan Fangyuan Hu Dongdong Li Jia He |
| author_facet |
Zhen Lin Hedong Han Wei Guo Xin Wei Zhijian Guo Shujie Zhai Shuai Li Yiming Ruan Fangyuan Hu Dongdong Li Jia He |
| author_sort |
Zhen Lin |
| title |
Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report |
| title_short |
Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report |
| title_full |
Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report |
| title_fullStr |
Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report |
| title_full_unstemmed |
Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report |
| title_sort |
atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report |
| publisher |
The Korean Association of Internal Medicine |
| publishDate |
2021 |
| url |
https://doaj.org/article/86f69258d89540dd945fcfa820725d39 |
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