Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model

Owing to neurite promoting, antioxidant and anti-inflammatory effects of Euxanthone (Eux), the investigation was aimed to probe the neuroprotective efficacy of Eux against traumatic spinal cord injury (t-SCI) in rats and whether Eux can improve neuropathic function in t-SCI.

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Autores principales: Yao Rubin, Ren Lirong, Wang Shiyong, Zhang Ming, Yang Kaishun
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
Materias:
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Acceso en línea:https://doaj.org/article/8711ebd06dcf4312b165ecf52d80ae36
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spelling oai:doaj.org-article:8711ebd06dcf4312b165ecf52d80ae362021-12-05T14:11:05ZEuxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model2081-693610.1515/tnsci-2021-0012https://doaj.org/article/8711ebd06dcf4312b165ecf52d80ae362021-03-01T00:00:00Zhttps://doi.org/10.1515/tnsci-2021-0012https://doaj.org/toc/2081-6936Owing to neurite promoting, antioxidant and anti-inflammatory effects of Euxanthone (Eux), the investigation was aimed to probe the neuroprotective efficacy of Eux against traumatic spinal cord injury (t-SCI) in rats and whether Eux can improve neuropathic function in t-SCI.Yao RubinRen LirongWang ShiyongZhang MingYang KaishunDe Gruyterarticleeuxanthonespinal cord injurynf-κbpi3kaktNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENTranslational Neuroscience, Vol 12, Iss 1, Pp 114-126 (2021)
institution DOAJ
collection DOAJ
language EN
topic euxanthone
spinal cord injury
nf-κb
pi3k
akt
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
spellingShingle euxanthone
spinal cord injury
nf-κb
pi3k
akt
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Yao Rubin
Ren Lirong
Wang Shiyong
Zhang Ming
Yang Kaishun
Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model
description Owing to neurite promoting, antioxidant and anti-inflammatory effects of Euxanthone (Eux), the investigation was aimed to probe the neuroprotective efficacy of Eux against traumatic spinal cord injury (t-SCI) in rats and whether Eux can improve neuropathic function in t-SCI.
format article
author Yao Rubin
Ren Lirong
Wang Shiyong
Zhang Ming
Yang Kaishun
author_facet Yao Rubin
Ren Lirong
Wang Shiyong
Zhang Ming
Yang Kaishun
author_sort Yao Rubin
title Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model
title_short Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model
title_full Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model
title_fullStr Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model
title_full_unstemmed Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model
title_sort euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and pi3k/akt signaling pathway in a rat model
publisher De Gruyter
publishDate 2021
url https://doaj.org/article/8711ebd06dcf4312b165ecf52d80ae36
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