Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia
Abstract Inflammation underpins aspects of insulin resistance and dysglycemia. Microbiota-derived cell wall components such as muropeptides or endotoxin can trigger changes in host immunity and metabolism. Specific peptidoglycan motifs promote metabolic tissue inflammation, lipolysis and insulin res...
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Autores principales: | Brittany M. Duggan, Kevin P. Foley, Brandyn D. Henriksbo, Joseph F. Cavallari, Akhilesh K. Tamrakar, Jonathan D. Schertzer |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/871e61fb014940668cc76f5a7be0fbe9 |
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