Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model

Combining different types of immune therapies might benefit certain patients. Here, the authors develop an autologous immune-humanized melanoma mouse model that allows the preclinical assessment of cancer cell–T cell interactions from each individual patient and the benefits of immunotherapies combi...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Henrik Jespersen, Mattias F. Lindberg, Marco Donia, Elin M. V. Söderberg, Rikke Andersen, Ulrich Keller, Lars Ny, Inge Marie Svane, Lisa M. Nilsson, Jonas A. Nilsson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/872053043156473e8e20cc09cdc48cb0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:872053043156473e8e20cc09cdc48cb0
record_format	dspace
spelling	oai:doaj.org-article:872053043156473e8e20cc09cdc48cb02021-12-02T15:38:43ZClinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model10.1038/s41467-017-00786-z2041-1723https://doaj.org/article/872053043156473e8e20cc09cdc48cb02017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00786-zhttps://doaj.org/toc/2041-1723Combining different types of immune therapies might benefit certain patients. Here, the authors develop an autologous immune-humanized melanoma mouse model that allows the preclinical assessment of cancer cell–T cell interactions from each individual patient and the benefits of immunotherapies combinations.Henrik JespersenMattias F. LindbergMarco DoniaElin M. V. SöderbergRikke AndersenUlrich KellerLars NyInge Marie SvaneLisa M. NilssonJonas A. NilssonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Henrik Jespersen Mattias F. Lindberg Marco Donia Elin M. V. Söderberg Rikke Andersen Ulrich Keller Lars Ny Inge Marie Svane Lisa M. Nilsson Jonas A. Nilsson Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
description	Combining different types of immune therapies might benefit certain patients. Here, the authors develop an autologous immune-humanized melanoma mouse model that allows the preclinical assessment of cancer cell–T cell interactions from each individual patient and the benefits of immunotherapies combinations.
format	article
author	Henrik Jespersen Mattias F. Lindberg Marco Donia Elin M. V. Söderberg Rikke Andersen Ulrich Keller Lars Ny Inge Marie Svane Lisa M. Nilsson Jonas A. Nilsson
author_facet	Henrik Jespersen Mattias F. Lindberg Marco Donia Elin M. V. Söderberg Rikke Andersen Ulrich Keller Lars Ny Inge Marie Svane Lisa M. Nilsson Jonas A. Nilsson
author_sort	Henrik Jespersen
title	Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
title_short	Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
title_full	Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
title_fullStr	Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
title_full_unstemmed	Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
title_sort	clinical responses to adoptive t-cell transfer can be modeled in an autologous immune-humanized mouse model
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/872053043156473e8e20cc09cdc48cb0
work_keys_str_mv	AT henrikjespersen clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT mattiasflindberg clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT marcodonia clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT elinmvsoderberg clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT rikkeandersen clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT ulrichkeller clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT larsny clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT ingemariesvane clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT lisamnilsson clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel AT jonasanilsson clinicalresponsestoadoptivetcelltransfercanbemodeledinanautologousimmunehumanizedmousemodel
_version_	1718386122558537728

Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model

Ejemplares similares