Immunological tolerance to muscle autoantigens involves peripheral deletion of autoreactive CD8+ T cells.
Muscle potentially represents the most abundant source of autoantigens of the body and can be targeted by a variety of severe autoimmune diseases. Yet, the mechanisms of immunological tolerance toward muscle autoantigens remain mostly unknown. We investigated this issue in transgenic SM-Ova mice tha...
Guardado en:
Autores principales: | Emilie Franck, Carole Bonneau, Laetitia Jean, Jean-Paul Henry, Yann Lacoume, Anna Salvetti, Olivier Boyer, Sahil Adriouch |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8724d9f9a2154f7da79f0107e5c6497b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Identification of autoreactive B cells with labeled nucleosomes
por: Vincent Gies, et al.
Publicado: (2017) -
Review of autoantigens in Sjögren’s syndrome: an update
por: Tong L, et al.
Publicado: (2017) -
Presence of diabetes autoantigens in extracellular vesicles derived from human islets
por: Craig P. Hasilo, et al.
Publicado: (2017) -
Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis
por: Tomoyuki Mutoh, et al.
Publicado: (2020) -
IMMUNE EPITOPE CONTINUUM OF THE PROTEIN RELATIONSHIPS, POLY- AND AUTOREACTIVITY OF ANTIBODIES
por: E. P. Kharchenko
Publicado: (2015)