The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications.

The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications.

Lantibiotics are peptides, produced by bacteria, that contain the noncanonical amino acid lanthionine and many of them exhibit antibacterial activities. The labyrinthopeptin A1 (LabyA1) is a prototype peptide of a novel class of carbacyclic lantibiotics. Here, we extensively evaluated its broad-spec...

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Autores principales: Geoffrey Férir, Mariya I Petrova, Graciela Andrei, Dana Huskens, Bart Hoorelbeke, Robert Snoeck, Jos Vanderleyden, Jan Balzarini, Stefan Bartoschek, Mark Brönstrup, Roderich D Süssmuth, Dominique Schols
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/872bea6f6dfd45b8b8ca202f5c18c5d9
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