The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications.
Lantibiotics are peptides, produced by bacteria, that contain the noncanonical amino acid lanthionine and many of them exhibit antibacterial activities. The labyrinthopeptin A1 (LabyA1) is a prototype peptide of a novel class of carbacyclic lantibiotics. Here, we extensively evaluated its broad-spec...
Enregistré dans:
Auteurs principaux: | Geoffrey Férir, Mariya I Petrova, Graciela Andrei, Dana Huskens, Bart Hoorelbeke, Robert Snoeck, Jos Vanderleyden, Jan Balzarini, Stefan Bartoschek, Mark Brönstrup, Roderich D Süssmuth, Dominique Schols |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/872bea6f6dfd45b8b8ca202f5c18c5d9 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity.
par: Jan Balzarini, et autres
Publié: (2013) -
SYNTHESIS OF DIBENZYLBUTANEDIOL LIGNANS AND THEIR ANTI-HIV, ANTI-HSV, ANTI-TUMOR ACTIVITIES
par: MU XIA,YA, et autres
Publié: (2009) -
Lignosulfonic acid exhibits broadly anti-HIV-1 activity--potential as a microbicide candidate for the prevention of HIV-1 sexual transmission.
par: Min Qiu, et autres
Publié: (2012) -
Lantibiotic production is a burden for the producing staphylococci
par: Patrick Ebner, et autres
Publié: (2018) -
The combination therapy of oncolytic HSV-1 armed with anti-PD-1 antibody and IL-12 enhances anti-tumor efficacy
par: Xin Xie, et autres
Publié: (2022)