2D and 3D-organized cardiac cells shows differences in cellular morphology, adhesion junctions, presence of myofibrils and protein expression.

Cardiac cells are organized in vivo in a complex tridimensional structural organization that is crucial for heart function. While in vitro studies can reveal details about cardiac cell biology, usually cells are grown on simplified two-dimensional (2D) environments. To address these differences, we...

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Main Authors: Carolina Pontes Soares, Victor Midlej, Maria Eduarda Weschollek de Oliveira, Marlene Benchimol, Manoel Luis Costa, Cláudia Mermelstein
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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Online Access:https://doaj.org/article/872f8dd0c0bf40b5bb9ef4dc7b6c9be8
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