DropletQC: improved identification of empty droplets and damaged cells in single-cell RNA-seq data

Abstract Background Advances in droplet-based single-cell RNA-sequencing (scRNA-seq) have dramatically increased throughput, allowing tens of thousands of cells to be routinely sequenced in a single experiment. In addition to cells, droplets capture cell-free “ambient” RNA predominantly caused by ly...

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Autores principales: Walter Muskovic, Joseph E. Powell
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/87314464a784446a98f63d2b1ca32ddb
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