Critical angle reflection imaging for quantification of molecular interactions on glass surface

Here, the authors present a method for quantifying molecular interactions on a glass surface, based on measuring surface refractive index changes via the reflectivity near the critical angle. They demonstrate tunable sensitivity and dynamic range, deep vertical sensing range, also for intracellular...

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Detalles Bibliográficos
Autores principales:	Guangzhong Ma, Runli Liang, Zijian Wan, Shaopeng Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/873586456517485397e2392c36e5a4df
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spelling	oai:doaj.org-article:873586456517485397e2392c36e5a4df2021-12-02T17:52:38ZCritical angle reflection imaging for quantification of molecular interactions on glass surface10.1038/s41467-021-23730-82041-1723https://doaj.org/article/873586456517485397e2392c36e5a4df2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23730-8https://doaj.org/toc/2041-1723Here, the authors present a method for quantifying molecular interactions on a glass surface, based on measuring surface refractive index changes via the reflectivity near the critical angle. They demonstrate tunable sensitivity and dynamic range, deep vertical sensing range, also for intracellular signals.Guangzhong MaRunli LiangZijian WanShaopeng WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Guangzhong Ma Runli Liang Zijian Wan Shaopeng Wang Critical angle reflection imaging for quantification of molecular interactions on glass surface
description	Here, the authors present a method for quantifying molecular interactions on a glass surface, based on measuring surface refractive index changes via the reflectivity near the critical angle. They demonstrate tunable sensitivity and dynamic range, deep vertical sensing range, also for intracellular signals.
format	article
author	Guangzhong Ma Runli Liang Zijian Wan Shaopeng Wang
author_facet	Guangzhong Ma Runli Liang Zijian Wan Shaopeng Wang
author_sort	Guangzhong Ma
title	Critical angle reflection imaging for quantification of molecular interactions on glass surface
title_short	Critical angle reflection imaging for quantification of molecular interactions on glass surface
title_full	Critical angle reflection imaging for quantification of molecular interactions on glass surface
title_fullStr	Critical angle reflection imaging for quantification of molecular interactions on glass surface
title_full_unstemmed	Critical angle reflection imaging for quantification of molecular interactions on glass surface
title_sort	critical angle reflection imaging for quantification of molecular interactions on glass surface
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/873586456517485397e2392c36e5a4df
work_keys_str_mv	AT guangzhongma criticalanglereflectionimagingforquantificationofmolecularinteractionsonglasssurface AT runliliang criticalanglereflectionimagingforquantificationofmolecularinteractionsonglasssurface AT zijianwan criticalanglereflectionimagingforquantificationofmolecularinteractionsonglasssurface AT shaopengwang criticalanglereflectionimagingforquantificationofmolecularinteractionsonglasssurface
_version_	1718379177764192256

Critical angle reflection imaging for quantification of molecular interactions on glass surface

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