Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity

Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity

Serology is an important way to monitor SARS-CoV-2 infection in the population and support vaccine development. Here the authors develop a multiplex immunoassay including spike and nucleocapsid proteins of SARS-CoV-2 and the endemic human coronaviruses with high specificity and sensitivity.

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Autores principales: Matthias Becker, Monika Strengert, Daniel Junker, Philipp D. Kaiser, Tobias Kerrinnes, Bjoern Traenkle, Heiko Dinter, Julia Häring, Stéphane Ghozzi, Anne Zeck, Frank Weise, Andreas Peter, Sebastian Hörber, Simon Fink, Felix Ruoff, Alex Dulovic, Tamam Bakchoul, Armin Baillot, Stefan Lohse, Markus Cornberg, Thomas Illig, Jens Gottlieb, Sigrun Smola, André Karch, Klaus Berger, Hans-Georg Rammensee, Katja Schenke-Layland, Annika Nelde, Melanie Märklin, Jonas S. Heitmann, Juliane S. Walz, Markus Templin, Thomas O. Joos, Ulrich Rothbauer, Gérard Krause, Nicole Schneiderhan-Marra
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
Q
Acceso en línea:https://doaj.org/article/873a2271e3d141e88ecbd175b0df6297
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spelling oai:doaj.org-article:873a2271e3d141e88ecbd175b0df62972021-12-02T10:52:47ZExploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity10.1038/s41467-021-20973-32041-1723https://doaj.org/article/873a2271e3d141e88ecbd175b0df62972021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20973-3https://doaj.org/toc/2041-1723Serology is an important way to monitor SARS-CoV-2 infection in the population and support vaccine development. Here the authors develop a multiplex immunoassay including spike and nucleocapsid proteins of SARS-CoV-2 and the endemic human coronaviruses with high specificity and sensitivity.Matthias BeckerMonika StrengertDaniel JunkerPhilipp D. KaiserTobias KerrinnesBjoern TraenkleHeiko DinterJulia HäringStéphane GhozziAnne ZeckFrank WeiseAndreas PeterSebastian HörberSimon FinkFelix RuoffAlex DulovicTamam BakchoulArmin BaillotStefan LohseMarkus CornbergThomas IlligJens GottliebSigrun SmolaAndré KarchKlaus BergerHans-Georg RammenseeKatja Schenke-LaylandAnnika NeldeMelanie MärklinJonas S. HeitmannJuliane S. WalzMarkus TemplinThomas O. JoosUlrich RothbauerGérard KrauseNicole Schneiderhan-MarraNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Matthias Becker
Monika Strengert
Daniel Junker
Philipp D. Kaiser
Tobias Kerrinnes
Bjoern Traenkle
Heiko Dinter
Julia Häring
Stéphane Ghozzi
Anne Zeck
Frank Weise
Andreas Peter
Sebastian Hörber
Simon Fink
Felix Ruoff
Alex Dulovic
Tamam Bakchoul
Armin Baillot
Stefan Lohse
Markus Cornberg
Thomas Illig
Jens Gottlieb
Sigrun Smola
André Karch
Klaus Berger
Hans-Georg Rammensee
Katja Schenke-Layland
Annika Nelde
Melanie Märklin
Jonas S. Heitmann
Juliane S. Walz
Markus Templin
Thomas O. Joos
Ulrich Rothbauer
Gérard Krause
Nicole Schneiderhan-Marra
Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity
description Serology is an important way to monitor SARS-CoV-2 infection in the population and support vaccine development. Here the authors develop a multiplex immunoassay including spike and nucleocapsid proteins of SARS-CoV-2 and the endemic human coronaviruses with high specificity and sensitivity.
format article
author Matthias Becker
Monika Strengert
Daniel Junker
Philipp D. Kaiser
Tobias Kerrinnes
Bjoern Traenkle
Heiko Dinter
Julia Häring
Stéphane Ghozzi
Anne Zeck
Frank Weise
Andreas Peter
Sebastian Hörber
Simon Fink
Felix Ruoff
Alex Dulovic
Tamam Bakchoul
Armin Baillot
Stefan Lohse
Markus Cornberg
Thomas Illig
Jens Gottlieb
Sigrun Smola
André Karch
Klaus Berger
Hans-Georg Rammensee
Katja Schenke-Layland
Annika Nelde
Melanie Märklin
Jonas S. Heitmann
Juliane S. Walz
Markus Templin
Thomas O. Joos
Ulrich Rothbauer
Gérard Krause
Nicole Schneiderhan-Marra
author_facet Matthias Becker
Monika Strengert
Daniel Junker
Philipp D. Kaiser
Tobias Kerrinnes
Bjoern Traenkle
Heiko Dinter
Julia Häring
Stéphane Ghozzi
Anne Zeck
Frank Weise
Andreas Peter
Sebastian Hörber
Simon Fink
Felix Ruoff
Alex Dulovic
Tamam Bakchoul
Armin Baillot
Stefan Lohse
Markus Cornberg
Thomas Illig
Jens Gottlieb
Sigrun Smola
André Karch
Klaus Berger
Hans-Georg Rammensee
Katja Schenke-Layland
Annika Nelde
Melanie Märklin
Jonas S. Heitmann
Juliane S. Walz
Markus Templin
Thomas O. Joos
Ulrich Rothbauer
Gérard Krause
Nicole Schneiderhan-Marra
author_sort Matthias Becker
title Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity
title_short Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity
title_full Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity
title_fullStr Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity
title_full_unstemmed Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity
title_sort exploring beyond clinical routine sars-cov-2 serology using multicov-ab to evaluate endemic coronavirus cross-reactivity
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/873a2271e3d141e88ecbd175b0df6297
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