Clinical and Immunological Features of Human BCL10 Deficiency

Clinical and Immunological Features of Human BCL10 Deficiency

The CARD-BCL10-MALT1 (CBM) complex is critical for the proper assembly of human immune responses. The clinical and immunological consequences of deficiencies in some of its components such as CARD9, CARD11, and MALT1 have been elucidated in detail. However, the scarcity of BCL10 deficient patients h...

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Main Authors: Blanca Garcia-Solis, Ana Van Den Rym, Jareb J. Pérez-Caraballo, Abdulwahab Al–Ayoubi, Anas M. Alazami, Lazaro Lorenzo, Carolina Cubillos-Zapata, Eduardo López-Collazo, Antonio Pérez-Martínez, Luis M. Allende, Janet Markle, Miguel Fernández-Arquero, Silvia Sánchez-Ramón, Maria J. Recio, Jean-Laurent Casanova, Reem Mohammed, Rubén Martinez-Barricarte, Rebeca Pérez de Diego
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
primary immunodeficiency
combined immunodeficiency
BCL10
autosomal recessive
mass cytometry
computational immunology
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/8741b9bb80a4423bab400712dd1659fa
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https://doaj.org/article/8741b9bb80a4423bab400712dd1659fa

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