A Mendelian randomization study of the effects of blood lipids on breast cancer risk

The link between circulating lipids and breast cancer risk is complex. Here, the authors utilise data from more than 400,000 participants in two-sample Mendelian randomization to assess the link between blood lipids and breast cancer risk, and they find risk-promoting effects of raised LDL-cholester...

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Autores principales: Christoph Nowak, Johan Ärnlöv
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/8742aca1703744a4a49203e403ab0907
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spelling oai:doaj.org-article:8742aca1703744a4a49203e403ab09072021-12-02T16:49:16ZA Mendelian randomization study of the effects of blood lipids on breast cancer risk10.1038/s41467-018-06467-92041-1723https://doaj.org/article/8742aca1703744a4a49203e403ab09072018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06467-9https://doaj.org/toc/2041-1723The link between circulating lipids and breast cancer risk is complex. Here, the authors utilise data from more than 400,000 participants in two-sample Mendelian randomization to assess the link between blood lipids and breast cancer risk, and they find risk-promoting effects of raised LDL-cholesterol and CETP-mediated raised HDL-cholesterol.Christoph NowakJohan ÄrnlövNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Christoph Nowak
Johan Ärnlöv
A Mendelian randomization study of the effects of blood lipids on breast cancer risk
description The link between circulating lipids and breast cancer risk is complex. Here, the authors utilise data from more than 400,000 participants in two-sample Mendelian randomization to assess the link between blood lipids and breast cancer risk, and they find risk-promoting effects of raised LDL-cholesterol and CETP-mediated raised HDL-cholesterol.
format article
author Christoph Nowak
Johan Ärnlöv
author_facet Christoph Nowak
Johan Ärnlöv
author_sort Christoph Nowak
title A Mendelian randomization study of the effects of blood lipids on breast cancer risk
title_short A Mendelian randomization study of the effects of blood lipids on breast cancer risk
title_full A Mendelian randomization study of the effects of blood lipids on breast cancer risk
title_fullStr A Mendelian randomization study of the effects of blood lipids on breast cancer risk
title_full_unstemmed A Mendelian randomization study of the effects of blood lipids on breast cancer risk
title_sort mendelian randomization study of the effects of blood lipids on breast cancer risk
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/8742aca1703744a4a49203e403ab0907
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AT johanarnlov mendelianrandomizationstudyoftheeffectsofbloodlipidsonbreastcancerrisk
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