A Mendelian randomization study of the effects of blood lipids on breast cancer risk
The link between circulating lipids and breast cancer risk is complex. Here, the authors utilise data from more than 400,000 participants in two-sample Mendelian randomization to assess the link between blood lipids and breast cancer risk, and they find risk-promoting effects of raised LDL-cholester...
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Nature Portfolio
2018
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oai:doaj.org-article:8742aca1703744a4a49203e403ab09072021-12-02T16:49:16ZA Mendelian randomization study of the effects of blood lipids on breast cancer risk10.1038/s41467-018-06467-92041-1723https://doaj.org/article/8742aca1703744a4a49203e403ab09072018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06467-9https://doaj.org/toc/2041-1723The link between circulating lipids and breast cancer risk is complex. Here, the authors utilise data from more than 400,000 participants in two-sample Mendelian randomization to assess the link between blood lipids and breast cancer risk, and they find risk-promoting effects of raised LDL-cholesterol and CETP-mediated raised HDL-cholesterol.Christoph NowakJohan ÄrnlövNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018) |
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Science Q Christoph Nowak Johan Ärnlöv A Mendelian randomization study of the effects of blood lipids on breast cancer risk |
description |
The link between circulating lipids and breast cancer risk is complex. Here, the authors utilise data from more than 400,000 participants in two-sample Mendelian randomization to assess the link between blood lipids and breast cancer risk, and they find risk-promoting effects of raised LDL-cholesterol and CETP-mediated raised HDL-cholesterol. |
format |
article |
author |
Christoph Nowak Johan Ärnlöv |
author_facet |
Christoph Nowak Johan Ärnlöv |
author_sort |
Christoph Nowak |
title |
A Mendelian randomization study of the effects of blood lipids on breast cancer risk |
title_short |
A Mendelian randomization study of the effects of blood lipids on breast cancer risk |
title_full |
A Mendelian randomization study of the effects of blood lipids on breast cancer risk |
title_fullStr |
A Mendelian randomization study of the effects of blood lipids on breast cancer risk |
title_full_unstemmed |
A Mendelian randomization study of the effects of blood lipids on breast cancer risk |
title_sort |
mendelian randomization study of the effects of blood lipids on breast cancer risk |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/8742aca1703744a4a49203e403ab0907 |
work_keys_str_mv |
AT christophnowak amendelianrandomizationstudyoftheeffectsofbloodlipidsonbreastcancerrisk AT johanarnlov amendelianrandomizationstudyoftheeffectsofbloodlipidsonbreastcancerrisk AT christophnowak mendelianrandomizationstudyoftheeffectsofbloodlipidsonbreastcancerrisk AT johanarnlov mendelianrandomizationstudyoftheeffectsofbloodlipidsonbreastcancerrisk |
_version_ |
1718383407106359296 |