Tofacitinib Ameliorates Retinal Vascular Leakage in a Murine Model of Diabetic Retinopathy with Type 2 Diabetes

We have previously reported that inhibition of the Janus kinase 1 (JAK1) signaling ameliorates IL-17A-mediated blood-retinal barrier (BRB) dysfunction. Higher levels of IL-17A have been observed in the blood and intraocular fluids in patients with diabetic retinopathy (DR), in particular those with...

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Bibliographic Details
Main Authors: Eimear M. Byrne, María Llorián-Salvador, Timothy J. Lyons, Mei Chen, Heping Xu
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/87449f3a925a48d2b1438066aeb4b0e7
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