THE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS

Objective: to measure cell susceptibility of peripheral blood leukocytes to interferon-α2 in vitro at children during the acute period in 1 and 6 months after infectious mononucleosis caused by the Epstein–Barr virus. 47 children aged 4–6 years with moderately severe form of the disease in the acute...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	L. M. Kurtasova, N. A. Shakina, L. A. Ikkes
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2017
Materias:	cell susceptibility white blood cells interferon epstein–barr virus Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/8746d6edec3e4ffa8a973685c067c06e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8746d6edec3e4ffa8a973685c067c06e
record_format	dspace
spelling	oai:doaj.org-article:8746d6edec3e4ffa8a973685c067c06e2021-11-22T07:09:48ZTHE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS2220-76192313-739810.15789/2220-7619-2017-1-85-90https://doaj.org/article/8746d6edec3e4ffa8a973685c067c06e2017-03-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/483https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Objective: to measure cell susceptibility of peripheral blood leukocytes to interferon-α2 in vitro at children during the acute period in 1 and 6 months after infectious mononucleosis caused by the Epstein–Barr virus. 47 children aged 4–6 years with moderately severe form of the disease in the acute period of infectious mononucleosis caused by the Epstein–Barr virus (EBV) were examined, as well as in 1 month (n = 17) and 6 months (n = 11) after the disease. The focus group consisted of 36 nearly healthy children. The cell susceptibility to interferon-α2 in vitro was determined by the method of Kurtasova L.M. et al. (2007). Chemiluminescence of blood leukocytes was studied by De Sole et al. (1983). The susceptibility change of peripheral blood leukocytes to interferon-α2 in vitro at children with infectious mononucleosis caused by Epstein–Barr virus in dynamics of the disease has been revealed. The expansion of the range of cell susceptibility to interferon-α2 in 6 months after the disease has been enclosed. The dependence of the susceptibility of peripheral blood leukocytes to interferon-α2 in vitro on the dose and the period of the disease has been fixed.L. M. KurtasovaN. A. ShakinaL. A. IkkesSankt-Peterburg : NIIÈM imeni Pasteraarticlecell susceptibilitywhite blood cellsinterferonepstein–barr virusInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 7, Iss 1, Pp 85-90 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	cell susceptibility white blood cells interferon epstein–barr virus Infectious and parasitic diseases RC109-216
spellingShingle	cell susceptibility white blood cells interferon epstein–barr virus Infectious and parasitic diseases RC109-216 L. M. Kurtasova N. A. Shakina L. A. Ikkes THE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS
description	Objective: to measure cell susceptibility of peripheral blood leukocytes to interferon-α2 in vitro at children during the acute period in 1 and 6 months after infectious mononucleosis caused by the Epstein–Barr virus. 47 children aged 4–6 years with moderately severe form of the disease in the acute period of infectious mononucleosis caused by the Epstein–Barr virus (EBV) were examined, as well as in 1 month (n = 17) and 6 months (n = 11) after the disease. The focus group consisted of 36 nearly healthy children. The cell susceptibility to interferon-α2 in vitro was determined by the method of Kurtasova L.M. et al. (2007). Chemiluminescence of blood leukocytes was studied by De Sole et al. (1983). The susceptibility change of peripheral blood leukocytes to interferon-α2 in vitro at children with infectious mononucleosis caused by Epstein–Barr virus in dynamics of the disease has been revealed. The expansion of the range of cell susceptibility to interferon-α2 in 6 months after the disease has been enclosed. The dependence of the susceptibility of peripheral blood leukocytes to interferon-α2 in vitro on the dose and the period of the disease has been fixed.
format	article
author	L. M. Kurtasova N. A. Shakina L. A. Ikkes
author_facet	L. M. Kurtasova N. A. Shakina L. A. Ikkes
author_sort	L. M. Kurtasova
title	THE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS
title_short	THE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS
title_full	THE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS
title_fullStr	THE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS
title_full_unstemmed	THE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS
title_sort	peripheral blood leukocytes susceptibility to interferon-α2 in vitro change amongst children with infectious mononucleosis
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2017
url	https://doaj.org/article/8746d6edec3e4ffa8a973685c067c06e
work_keys_str_mv	AT lmkurtasova theperipheralbloodleukocytessusceptibilitytointerferona2invitrochangeamongstchildrenwithinfectiousmononucleosis AT nashakina theperipheralbloodleukocytessusceptibilitytointerferona2invitrochangeamongstchildrenwithinfectiousmononucleosis AT laikkes theperipheralbloodleukocytessusceptibilitytointerferona2invitrochangeamongstchildrenwithinfectiousmononucleosis AT lmkurtasova peripheralbloodleukocytessusceptibilitytointerferona2invitrochangeamongstchildrenwithinfectiousmononucleosis AT nashakina peripheralbloodleukocytessusceptibilitytointerferona2invitrochangeamongstchildrenwithinfectiousmononucleosis AT laikkes peripheralbloodleukocytessusceptibilitytointerferona2invitrochangeamongstchildrenwithinfectiousmononucleosis
_version_	1718418052968611840

THE PERIPHERAL BLOOD LEUKOCYTES SUSCEPTIBILITY TO INTERFERON-α2 IN VITRO CHANGE AMONGST CHILDREN WITH INFECTIOUS MONONUCLEOSIS

Ejemplares similares