Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine

Vaccine mismatch and changes in antigenicity due to vaccine strain egg adaptation can affect seasonal influenza vaccine effectiveness. Here, Gouma et al. show that the egg-adapted 3c3.A H3N2 vaccine strain elicits antibodies with limited reactivity to a wildtype 3c3.A strain and currently circulatin...

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Autores principales:	Sigrid Gouma, Madison Weirick, Scott E. Hensley
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/874ba893d686469880ee36a072d48d94
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spelling	oai:doaj.org-article:874ba893d686469880ee36a072d48d942021-12-02T16:50:20ZAntigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine10.1038/s41467-020-16183-y2041-1723https://doaj.org/article/874ba893d686469880ee36a072d48d942020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16183-yhttps://doaj.org/toc/2041-1723Vaccine mismatch and changes in antigenicity due to vaccine strain egg adaptation can affect seasonal influenza vaccine effectiveness. Here, Gouma et al. show that the egg-adapted 3c3.A H3N2 vaccine strain elicits antibodies with limited reactivity to a wildtype 3c3.A strain and currently circulating 3c2.A H3N2 strains.Sigrid GoumaMadison WeirickScott E. HensleyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-5 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sigrid Gouma Madison Weirick Scott E. Hensley Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine
description	Vaccine mismatch and changes in antigenicity due to vaccine strain egg adaptation can affect seasonal influenza vaccine effectiveness. Here, Gouma et al. show that the egg-adapted 3c3.A H3N2 vaccine strain elicits antibodies with limited reactivity to a wildtype 3c3.A strain and currently circulating 3c2.A H3N2 strains.
format	article
author	Sigrid Gouma Madison Weirick Scott E. Hensley
author_facet	Sigrid Gouma Madison Weirick Scott E. Hensley
author_sort	Sigrid Gouma
title	Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine
title_short	Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine
title_full	Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine
title_fullStr	Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine
title_full_unstemmed	Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine
title_sort	antigenic assessment of the h3n2 component of the 2019-2020 northern hemisphere influenza vaccine
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/874ba893d686469880ee36a072d48d94
work_keys_str_mv	AT sigridgouma antigenicassessmentoftheh3n2componentofthe20192020northernhemisphereinfluenzavaccine AT madisonweirick antigenicassessmentoftheh3n2componentofthe20192020northernhemisphereinfluenzavaccine AT scottehensley antigenicassessmentoftheh3n2componentofthe20192020northernhemisphereinfluenzavaccine
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Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine

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