Oxidative stress-induced impairment of trophoblast function causes preeclampsia through the unfolded protein response pathway

Oxidative stress-induced impairment of trophoblast function causes preeclampsia through the unfolded protein response pathway

Abstract Pre-eclampsia (PE) is a pregnancy-specific disorder, characterized by hypertension and proteinuria. In PE, trophoblasts mediated inadequate remodeling of uterine spiral arteries seem to interrupt uteroplacental blood flow, one of the hallmarks in the early onset of PE (EO-PE). This, in turn...

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Autores principales: Indrani Mukherjee, Ruby Dhar, Sunil Singh, Jai Bhagwan Sharma, Tapas Chandra Nag, Asit Ranjan Mridha, Parul Jaiswal, Subhrajit Biswas, Subhradip Karmakar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/875a04a1c7954d4e9504a5cbd7bff77b
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