Methylation of BRCA1 promoter region is associated with unfavorable prognosis in women with early-stage breast cancer.

Methylation of BRCA1 promoter region is associated with unfavorable prognosis in women with early-stage breast cancer.

BRCA1-associated breast cancers are associated with particular features such as early onset, poor histological differentiation, and hormone receptor negativity. Previous studies conducted in Taiwanese population showed that the mutation of BRCA1 gene does not play a significant role in the occurrenc...

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Autores principales: Nicholas C Hsu, Ya-Fang Huang, Kazunari K Yokoyama, Pei-Yi Chu, Fang-Ming Chen, Ming-Feng Hou
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/875a407dc2c645dea6f376175d4717ee
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