CLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS

We studied the changes in content of the autoantibodies to the antigens from nervous tissue was performed in the employees contacting with, metallic mercury, in the patients with, the mercury intoxication, at the different stages of the pathological process. It was found that small increase of conce...

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Autores principales:	G. M. Bodienkova, E. V. Boklazhenko, E. V. Katamanova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	chronic mercury intoxication autoantibodies to antigens of nervous tissue employees Science Q
Acceso en línea:	https://doaj.org/article/87615e1d32b845d4806caeb2f26411b3
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spelling	oai:doaj.org-article:87615e1d32b845d4806caeb2f26411b32021-11-23T06:14:18ZCLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS2541-94202587-9596https://doaj.org/article/87615e1d32b845d4806caeb2f26411b32012-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/774https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596We studied the changes in content of the autoantibodies to the antigens from nervous tissue was performed in the employees contacting with, metallic mercury, in the patients with, the mercury intoxication, at the different stages of the pathological process. It was found that small increase of concentrations of the autoantibodies to the protein S-100 in the "practically" healthy employees may be considered, as the protective physiological mechanism.. Influence of the mercury on the employees' organisms promotes the change of autoimmune reactions that are characterized by the increase of content of antibodies to the brain-specific proteins in blood serum.. The decrease of the antibody levels in patients with chronic mercury intoxication, in remote period and the increase of severity of pathological process testifies to the dysregulation in the immune system.. It was determined, that the increase of autoantibodies to MAG was typical only for the patients with chronic mercury intoxication. (CMI), thereby, higher levels of autoantibodies were observed in the patients with more dominated cognitive disorders in comparison with the patients with more dominated asthenic disorders. In healthy employees and the ones of "risk group" concentrations of autoantibodies to MAG were at the level of control. Increased, levels of autoantibodies to MAG testify to the formation of neurodegenerative changes and. are one of the diagnostic criteria.G. M. BodienkovaE. V. BoklazhenkoE. V. KatamanovaScientific Сentre for Family Health and Human Reproduction Problemsarticlechronic mercury intoxicationautoantibodies to antigens of nervous tissueemployeesScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2(1), Pp 20-23 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	chronic mercury intoxication autoantibodies to antigens of nervous tissue employees Science Q
spellingShingle	chronic mercury intoxication autoantibodies to antigens of nervous tissue employees Science Q G. M. Bodienkova E. V. Boklazhenko E. V. Katamanova CLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS
description	We studied the changes in content of the autoantibodies to the antigens from nervous tissue was performed in the employees contacting with, metallic mercury, in the patients with, the mercury intoxication, at the different stages of the pathological process. It was found that small increase of concentrations of the autoantibodies to the protein S-100 in the "practically" healthy employees may be considered, as the protective physiological mechanism.. Influence of the mercury on the employees' organisms promotes the change of autoimmune reactions that are characterized by the increase of content of antibodies to the brain-specific proteins in blood serum.. The decrease of the antibody levels in patients with chronic mercury intoxication, in remote period and the increase of severity of pathological process testifies to the dysregulation in the immune system.. It was determined, that the increase of autoantibodies to MAG was typical only for the patients with chronic mercury intoxication. (CMI), thereby, higher levels of autoantibodies were observed in the patients with more dominated cognitive disorders in comparison with the patients with more dominated asthenic disorders. In healthy employees and the ones of "risk group" concentrations of autoantibodies to MAG were at the level of control. Increased, levels of autoantibodies to MAG testify to the formation of neurodegenerative changes and. are one of the diagnostic criteria.
format	article
author	G. M. Bodienkova E. V. Boklazhenko E. V. Katamanova
author_facet	G. M. Bodienkova E. V. Boklazhenko E. V. Katamanova
author_sort	G. M. Bodienkova
title	CLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS
title_short	CLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS
title_full	CLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS
title_fullStr	CLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS
title_full_unstemmed	CLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS
title_sort	clinical value of regulatory autoantibodies in development of neurointoxication with metallic mercury vapours
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/87615e1d32b845d4806caeb2f26411b3
work_keys_str_mv	AT gmbodienkova clinicalvalueofregulatoryautoantibodiesindevelopmentofneurointoxicationwithmetallicmercuryvapours AT evboklazhenko clinicalvalueofregulatoryautoantibodiesindevelopmentofneurointoxicationwithmetallicmercuryvapours AT evkatamanova clinicalvalueofregulatoryautoantibodiesindevelopmentofneurointoxicationwithmetallicmercuryvapours
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CLINICAL VALUE OF REGULATORY AUTOANTIBODIES IN DEVELOPMENT OF NEUROINTOXICATION WITH METALLIC MERCURY VAPOURS

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