The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

Gastrointestinal infection with parasitic helminths can protect against mucosal diseases via impacting on the microbiome. Here the authors show that ES-62, a product secreted by a tissue-resident helminth modulates the host gut microbiome to protect against inflammatory arthritis in a mouse model.

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Auteurs principaux:	James Doonan, Anuradha Tarafdar, Miguel A. Pineda, Felicity E. Lumb, Jenny Crowe, Aneesah M. Khan, Paul A. Hoskisson, Margaret M. Harnett, William Harnett
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/8765710fbb1b48aea36aa040ff1dbf77
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spelling	oai:doaj.org-article:8765710fbb1b48aea36aa040ff1dbf772021-12-02T15:35:30ZThe parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis10.1038/s41467-019-09361-02041-1723https://doaj.org/article/8765710fbb1b48aea36aa040ff1dbf772019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09361-0https://doaj.org/toc/2041-1723Gastrointestinal infection with parasitic helminths can protect against mucosal diseases via impacting on the microbiome. Here the authors show that ES-62, a product secreted by a tissue-resident helminth modulates the host gut microbiome to protect against inflammatory arthritis in a mouse model.James DoonanAnuradha TarafdarMiguel A. PinedaFelicity E. LumbJenny CroweAneesah M. KhanPaul A. HoskissonMargaret M. HarnettWilliam HarnettNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q James Doonan Anuradha Tarafdar Miguel A. Pineda Felicity E. Lumb Jenny Crowe Aneesah M. Khan Paul A. Hoskisson Margaret M. Harnett William Harnett The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
description	Gastrointestinal infection with parasitic helminths can protect against mucosal diseases via impacting on the microbiome. Here the authors show that ES-62, a product secreted by a tissue-resident helminth modulates the host gut microbiome to protect against inflammatory arthritis in a mouse model.
format	article
author	James Doonan Anuradha Tarafdar Miguel A. Pineda Felicity E. Lumb Jenny Crowe Aneesah M. Khan Paul A. Hoskisson Margaret M. Harnett William Harnett
author_facet	James Doonan Anuradha Tarafdar Miguel A. Pineda Felicity E. Lumb Jenny Crowe Aneesah M. Khan Paul A. Hoskisson Margaret M. Harnett William Harnett
author_sort	James Doonan
title	The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
title_short	The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
title_full	The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
title_fullStr	The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
title_full_unstemmed	The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
title_sort	parasitic worm product es-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8765710fbb1b48aea36aa040ff1dbf77
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The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

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