SYK kinase mediates brown fat differentiation and activation

Spleen protein tyrosine kinase (Syk) has so far been mainly studied in haematopoietic and immune cells. Here, the authors show that Syk also has a role in brown adipose tissue, where it regulates the formation of brown adipocytes and their thermogenic activation in response to β-adrenergic stimulati...

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Autores principales:	Marko Knoll, Sally Winther, Anirudh Natarajan, Huan Yang, Mengxi Jiang, Prathapan Thiru, Aliakbar Shahsafaei, Tony E. Chavarria, Dudley W. Lamming, Lei Sun, Jacob B. Hansen, Harvey F. Lodish
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/877a0b3be1764ea4bc9c077a7efffb20
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:877a0b3be1764ea4bc9c077a7efffb202021-12-02T14:40:47ZSYK kinase mediates brown fat differentiation and activation10.1038/s41467-017-02162-32041-1723https://doaj.org/article/877a0b3be1764ea4bc9c077a7efffb202017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02162-3https://doaj.org/toc/2041-1723Spleen protein tyrosine kinase (Syk) has so far been mainly studied in haematopoietic and immune cells. Here, the authors show that Syk also has a role in brown adipose tissue, where it regulates the formation of brown adipocytes and their thermogenic activation in response to β-adrenergic stimulation.Marko KnollSally WintherAnirudh NatarajanHuan YangMengxi JiangPrathapan ThiruAliakbar ShahsafaeiTony E. ChavarriaDudley W. LammingLei SunJacob B. HansenHarvey F. LodishNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marko Knoll Sally Winther Anirudh Natarajan Huan Yang Mengxi Jiang Prathapan Thiru Aliakbar Shahsafaei Tony E. Chavarria Dudley W. Lamming Lei Sun Jacob B. Hansen Harvey F. Lodish SYK kinase mediates brown fat differentiation and activation
description	Spleen protein tyrosine kinase (Syk) has so far been mainly studied in haematopoietic and immune cells. Here, the authors show that Syk also has a role in brown adipose tissue, where it regulates the formation of brown adipocytes and their thermogenic activation in response to β-adrenergic stimulation.
format	article
author	Marko Knoll Sally Winther Anirudh Natarajan Huan Yang Mengxi Jiang Prathapan Thiru Aliakbar Shahsafaei Tony E. Chavarria Dudley W. Lamming Lei Sun Jacob B. Hansen Harvey F. Lodish
author_facet	Marko Knoll Sally Winther Anirudh Natarajan Huan Yang Mengxi Jiang Prathapan Thiru Aliakbar Shahsafaei Tony E. Chavarria Dudley W. Lamming Lei Sun Jacob B. Hansen Harvey F. Lodish
author_sort	Marko Knoll
title	SYK kinase mediates brown fat differentiation and activation
title_short	SYK kinase mediates brown fat differentiation and activation
title_full	SYK kinase mediates brown fat differentiation and activation
title_fullStr	SYK kinase mediates brown fat differentiation and activation
title_full_unstemmed	SYK kinase mediates brown fat differentiation and activation
title_sort	syk kinase mediates brown fat differentiation and activation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/877a0b3be1764ea4bc9c077a7efffb20
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_version_	1718390185093234688

SYK kinase mediates brown fat differentiation and activation

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