Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models
Abstract Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti-ASD drug. Many reports have described the efficacy of intranasal OXT therapy to improve the core symptoms of patien...
Saved in:
Main Authors: | Machi Horiai, Ayano Otsuka, Shizu Hidema, Yuichi Hiraoka, Ryotaro Hayashi, Shinji Miyazaki, Tamio Furuse, Hiroaki Mizukami, Ryoichi Teruyama, Masaru Tamura, Haruhiko Bito, Yuko Maejima, Kenju Shimomura, Katsuhiko Nishimori |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/877a9c53f90b4d71bd32daef8a710a3a |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The OXTR Polymorphism Stratified the Correlation of Oxytocin and Glucose Homeostasis in Non-Diabetic Subjects
by: Chang HH, et al.
Published: (2019) -
No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.
by: Coren L Apicella, et al.
Published: (2010) -
Impact of sex, fat distribution and initial body weight on oxytocin’s body weight regulation
by: Yuko Maejima, et al.
Published: (2017) -
Quantitative cellular-resolution map of the oxytocin receptor in postnatally developing mouse brains
by: Kyra T. Newmaster, et al.
Published: (2020) -
Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousness
by: J. P. Gouin, et al.
Published: (2017)