Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China

Yanlei Zhang,1 Zusen Ye,1 Yun Fu,2 Zheng Zhang,1 Qiang Ye,1 Feichi Chen,1 Jianhua Cheng1 1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, People’s Republic of China; 2Department of Cardiac Surgery, The First Affiliate...

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Autores principales:	Zhang Y, Ye Z, Fu Y, Zhang Z, Ye Q, Chen F, Cheng J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	cardiac myxoma embolic complication ischemic stroke surgery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/877ac8af2bff413890f92cc95c94fbb4
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spelling	oai:doaj.org-article:877ac8af2bff413890f92cc95c94fbb42021-12-02T10:35:13ZCharacterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China1178-2021https://doaj.org/article/877ac8af2bff413890f92cc95c94fbb42021-01-01T00:00:00Zhttps://www.dovepress.com/characterizations-of-ischemic-stroke-complications-in-cardiac-myxoma-p-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Yanlei Zhang,1 Zusen Ye,1 Yun Fu,2 Zheng Zhang,1 Qiang Ye,1 Feichi Chen,1 Jianhua Cheng1 1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, People’s Republic of China; 2Department of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, People’s Republic of ChinaCorrespondence: Jianhua ChengDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou 325000, Zhejiang Province, People’s Republic of ChinaTel +86 577 55579365Fax +86 577 55578999Email chengjianhua@wmu.edu.cnBackground: Cardiac myxoma is the most common primary cardiac tumor. Even though it rarely causes a stroke, it is an important risk factor. Here, we compared our clinical experience in managing myxoma patients who developed stroke complications with those who did not present with this condition at the First Affiliated Hospital of Wenzhou Medical University.Patients and Methods: The medical records were reviewed of 160 cardiac myxoma patients who were treated in our facility from January 2006 to December 2019. They were separated into either a stroke group or non-stroke group.Results: Cardiac obstructive symptoms, embolic events and constitutional symptoms were observed in 92 (57.7%), 25 (15.6%) and 18 (11.2%) patients, respectively. Among 23 cardiac myxoma ischemic stroke patients, hypoesthesia (60.9%), hemiparesis (56.5%) and facial paresis (47.8%) were the three most common neurological symptoms. The middle cerebral artery (82.6%) was the most commonly affected vessel, whereas 73.9% of the ischemic patients had multiple stroke lesions. Binary logistic regression analysis showed that coronary heart disease and tumor sizes were independently associated in the stroke group (p < 0.05). The 10 years cumulative survival rate was 87.9% for all patients after surgical intervention. There was no significant difference in the 10 years cumulative survival rate between the two groups (80.0% vs 88.9%, p =0.274 > 0.05).Conclusion: The three most common neurological symptoms (hypoesthesia, hemiparesis and facial paresis), the middle cerebral artery and multiple lesions involvements were the definitive markers of patients afflicted with cardiac myxoma stroke. Small tumor sizes were independently associated with these patients. Surgical resection is a relatively safe procedure for treating both the stroke and non-stroke patients.Keywords: cardiac myxoma, embolic complication, ischemic stroke, surgeryZhang YYe ZFu YZhang ZYe QChen FCheng JDove Medical Pressarticlecardiac myxomaembolic complicationischemic strokesurgeryNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 17, Pp 33-40 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiac myxoma embolic complication ischemic stroke surgery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	cardiac myxoma embolic complication ischemic stroke surgery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Zhang Y Ye Z Fu Y Zhang Z Ye Q Chen F Cheng J Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China
description	Yanlei Zhang,1 Zusen Ye,1 Yun Fu,2 Zheng Zhang,1 Qiang Ye,1 Feichi Chen,1 Jianhua Cheng1 1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, People’s Republic of China; 2Department of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, People’s Republic of ChinaCorrespondence: Jianhua ChengDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou 325000, Zhejiang Province, People’s Republic of ChinaTel +86 577 55579365Fax +86 577 55578999Email chengjianhua@wmu.edu.cnBackground: Cardiac myxoma is the most common primary cardiac tumor. Even though it rarely causes a stroke, it is an important risk factor. Here, we compared our clinical experience in managing myxoma patients who developed stroke complications with those who did not present with this condition at the First Affiliated Hospital of Wenzhou Medical University.Patients and Methods: The medical records were reviewed of 160 cardiac myxoma patients who were treated in our facility from January 2006 to December 2019. They were separated into either a stroke group or non-stroke group.Results: Cardiac obstructive symptoms, embolic events and constitutional symptoms were observed in 92 (57.7%), 25 (15.6%) and 18 (11.2%) patients, respectively. Among 23 cardiac myxoma ischemic stroke patients, hypoesthesia (60.9%), hemiparesis (56.5%) and facial paresis (47.8%) were the three most common neurological symptoms. The middle cerebral artery (82.6%) was the most commonly affected vessel, whereas 73.9% of the ischemic patients had multiple stroke lesions. Binary logistic regression analysis showed that coronary heart disease and tumor sizes were independently associated in the stroke group (p < 0.05). The 10 years cumulative survival rate was 87.9% for all patients after surgical intervention. There was no significant difference in the 10 years cumulative survival rate between the two groups (80.0% vs 88.9%, p =0.274 > 0.05).Conclusion: The three most common neurological symptoms (hypoesthesia, hemiparesis and facial paresis), the middle cerebral artery and multiple lesions involvements were the definitive markers of patients afflicted with cardiac myxoma stroke. Small tumor sizes were independently associated with these patients. Surgical resection is a relatively safe procedure for treating both the stroke and non-stroke patients.Keywords: cardiac myxoma, embolic complication, ischemic stroke, surgery
format	article
author	Zhang Y Ye Z Fu Y Zhang Z Ye Q Chen F Cheng J
author_facet	Zhang Y Ye Z Fu Y Zhang Z Ye Q Chen F Cheng J
author_sort	Zhang Y
title	Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China
title_short	Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China
title_full	Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China
title_fullStr	Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China
title_full_unstemmed	Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China
title_sort	characterizations of ischemic stroke complications in cardiac myxoma patients at a single institution in eastern china
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/877ac8af2bff413890f92cc95c94fbb4
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Characterizations of Ischemic Stroke Complications in Cardiac Myxoma Patients at a Single Institution in Eastern China

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