NAFLD Nutritional Management: Results from a Multidisciplinary Approach

Introduction: Lifestyle changes are the mainstay treatment of nonalcoholic fatty liver disease (NAFLD). We aimed to assess the magnitude of weight loss in a group of NAFLD patients followed on a combined lifestyle intervention by a multidisciplinary team. Methods: Patients were assessed before and a...

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Autores principales:	Sara Raquel Osório Policarpo, Mariana V. Machado, David Barreira, Helena Cortez-Pinto
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	dietary intervention mediterranean diet nonalcoholic fatty liver disease multidisciplinary team weight loss Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/87803a00bd29439ea77eb4b21c0bde65
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spelling	oai:doaj.org-article:87803a00bd29439ea77eb4b21c0bde652021-12-02T12:40:23ZNAFLD Nutritional Management: Results from a Multidisciplinary Approach2341-45452387-195410.1159/000519932https://doaj.org/article/87803a00bd29439ea77eb4b21c0bde652021-12-01T00:00:00Zhttps://www.karger.com/Article/FullText/519932https://doaj.org/toc/2341-4545https://doaj.org/toc/2387-1954Introduction: Lifestyle changes are the mainstay treatment of nonalcoholic fatty liver disease (NAFLD). We aimed to assess the magnitude of weight loss in a group of NAFLD patients followed on a combined lifestyle intervention by a multidisciplinary team. Methods: Patients were assessed before and after a 12-month dietary intervention (Mediterranean diet aiming at weight loss). Patients who received a structured dietary plan along with general lifestyle recommendations were designated as the multidisciplinary treatment (MdT) group. Patients who declined follow-up still received general lifestyle recommendations and were designated as the conventional treatment group, being used as a control group. Results: From the 77 patients with documented NAFLD, 31.2% of patients were overweight and 55.8% obese; 66 patients constituted the MdT group and 11 the conventional treatment group. After 3 months, 89% of patients lost weight; at 6 months, 75.4% maintained the weight lost. At 12 months, 65% of patients still decreased their weight, with 92.2% of patients in the MdT group still maintaining a lower weight than baseline versus just 50% in the conventional group (p = 0.008). Only patients in the MdT group presented a weight loss higher than 10% (9.6%; n = 6). At 12 months patients in the MdT group presented an average reduction of 4.2 kg versus a reduction of just 0.6 kg in the conventional treatment group (p = 0.016). The MdT group, but not the conventional group, presented significant differences in liver enzymes at 12 months compared to baseline. Conclusion: Adherence to a multidisciplinary approach, compared to management solely by a hepatologist, in NAFLD patients, is effective with greater weight loss after a 12-month follow-up and a lower rate of weight gain recurrence.Sara Raquel Osório PolicarpoMariana V. MachadoDavid BarreiraHelena Cortez-PintoKarger Publishersarticledietary interventionmediterranean dietnonalcoholic fatty liver diseasemultidisciplinary teamweight lossDiseases of the digestive system. GastroenterologyRC799-869ENGE: Portuguese Journal of Gastroenterology, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	dietary intervention mediterranean diet nonalcoholic fatty liver disease multidisciplinary team weight loss Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	dietary intervention mediterranean diet nonalcoholic fatty liver disease multidisciplinary team weight loss Diseases of the digestive system. Gastroenterology RC799-869 Sara Raquel Osório Policarpo Mariana V. Machado David Barreira Helena Cortez-Pinto NAFLD Nutritional Management: Results from a Multidisciplinary Approach
description	Introduction: Lifestyle changes are the mainstay treatment of nonalcoholic fatty liver disease (NAFLD). We aimed to assess the magnitude of weight loss in a group of NAFLD patients followed on a combined lifestyle intervention by a multidisciplinary team. Methods: Patients were assessed before and after a 12-month dietary intervention (Mediterranean diet aiming at weight loss). Patients who received a structured dietary plan along with general lifestyle recommendations were designated as the multidisciplinary treatment (MdT) group. Patients who declined follow-up still received general lifestyle recommendations and were designated as the conventional treatment group, being used as a control group. Results: From the 77 patients with documented NAFLD, 31.2% of patients were overweight and 55.8% obese; 66 patients constituted the MdT group and 11 the conventional treatment group. After 3 months, 89% of patients lost weight; at 6 months, 75.4% maintained the weight lost. At 12 months, 65% of patients still decreased their weight, with 92.2% of patients in the MdT group still maintaining a lower weight than baseline versus just 50% in the conventional group (p = 0.008). Only patients in the MdT group presented a weight loss higher than 10% (9.6%; n = 6). At 12 months patients in the MdT group presented an average reduction of 4.2 kg versus a reduction of just 0.6 kg in the conventional treatment group (p = 0.016). The MdT group, but not the conventional group, presented significant differences in liver enzymes at 12 months compared to baseline. Conclusion: Adherence to a multidisciplinary approach, compared to management solely by a hepatologist, in NAFLD patients, is effective with greater weight loss after a 12-month follow-up and a lower rate of weight gain recurrence.
format	article
author	Sara Raquel Osório Policarpo Mariana V. Machado David Barreira Helena Cortez-Pinto
author_facet	Sara Raquel Osório Policarpo Mariana V. Machado David Barreira Helena Cortez-Pinto
author_sort	Sara Raquel Osório Policarpo
title	NAFLD Nutritional Management: Results from a Multidisciplinary Approach
title_short	NAFLD Nutritional Management: Results from a Multidisciplinary Approach
title_full	NAFLD Nutritional Management: Results from a Multidisciplinary Approach
title_fullStr	NAFLD Nutritional Management: Results from a Multidisciplinary Approach
title_full_unstemmed	NAFLD Nutritional Management: Results from a Multidisciplinary Approach
title_sort	nafld nutritional management: results from a multidisciplinary approach
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/87803a00bd29439ea77eb4b21c0bde65
work_keys_str_mv	AT sararaquelosoriopolicarpo nafldnutritionalmanagementresultsfromamultidisciplinaryapproach AT marianavmachado nafldnutritionalmanagementresultsfromamultidisciplinaryapproach AT davidbarreira nafldnutritionalmanagementresultsfromamultidisciplinaryapproach AT helenacortezpinto nafldnutritionalmanagementresultsfromamultidisciplinaryapproach
_version_	1718393749813329920

NAFLD Nutritional Management: Results from a Multidisciplinary Approach

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