Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines

Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines

ABSTRACT Epstein-Barr virus (EBV), an oncogenic herpesvirus, infects and transforms primary B cells into immortal lymphoblastoid cell lines (LCLs), providing a model for EBV-mediated tumorigenesis. EBV transformation stimulates robust homotypic aggregation, indicating that EBV induces molecules that...

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Autores principales: Lisa Grossman, Chris Chang, Joanne Dai, Pavel A. Nikitin, Dereje D. Jima, Sandeep S. Dave, Micah A. Luftig
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
CD226
DNAM-1
Epstein-Barr virus
LMP1
NF-κB
adhesion molecules
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/8781b480d55c41a78647de24435d873a
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