The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicans.

The fungal cell wall is the first point of interaction between an invading fungal pathogen and the host immune system. The outer layer of the cell wall is comprised of GPI anchored proteins, which are post-translationally modified by both N- and O-linked glycans. These glycans are important pathogen...

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Autores principales: Rebecca A Hall, Steven Bates, Megan D Lenardon, Donna M Maccallum, Jeanette Wagener, Douglas W Lowman, Michael D Kruppa, David L Williams, Frank C Odds, Alistair J P Brown, Neil A R Gow
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/878aec25a9854c68b2cfcadaef966aa8
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