Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides

The application of nanofibres formed from monomers of bacterial type IV pili in vitrohas proven to be complex. Here, the authors have overcome this limitation by using a reductionist approach to design a self-assembling pilin-based 20-mer peptide capable of forming a supramolecular beta sheet.

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Autores principales:	Tom Guterman, Micha Kornreich, Avigail Stern, Lihi Adler-Abramovich, Danny Porath, Roy Beck, Linda J. W. Shimon, Ehud Gazit
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/878c88710f364c8eb3dc72ffe6680c88
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spelling	oai:doaj.org-article:878c88710f364c8eb3dc72ffe6680c882021-12-02T17:32:06ZFormation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides10.1038/ncomms134822041-1723https://doaj.org/article/878c88710f364c8eb3dc72ffe6680c882016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13482https://doaj.org/toc/2041-1723The application of nanofibres formed from monomers of bacterial type IV pili in vitrohas proven to be complex. Here, the authors have overcome this limitation by using a reductionist approach to design a self-assembling pilin-based 20-mer peptide capable of forming a supramolecular beta sheet.Tom GutermanMicha KornreichAvigail SternLihi Adler-AbramovichDanny PorathRoy BeckLinda J. W. ShimonEhud GazitNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tom Guterman Micha Kornreich Avigail Stern Lihi Adler-Abramovich Danny Porath Roy Beck Linda J. W. Shimon Ehud Gazit Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides
description	The application of nanofibres formed from monomers of bacterial type IV pili in vitrohas proven to be complex. Here, the authors have overcome this limitation by using a reductionist approach to design a self-assembling pilin-based 20-mer peptide capable of forming a supramolecular beta sheet.
format	article
author	Tom Guterman Micha Kornreich Avigail Stern Lihi Adler-Abramovich Danny Porath Roy Beck Linda J. W. Shimon Ehud Gazit
author_facet	Tom Guterman Micha Kornreich Avigail Stern Lihi Adler-Abramovich Danny Porath Roy Beck Linda J. W. Shimon Ehud Gazit
author_sort	Tom Guterman
title	Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides
title_short	Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides
title_full	Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides
title_fullStr	Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides
title_full_unstemmed	Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides
title_sort	formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/878c88710f364c8eb3dc72ffe6680c88
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Formation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides

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