Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease

Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease

Abstract Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease of the central nervous system. Early treatment for PD is efficient; however, long-term systemic medication commonly leads to deleterious side-effects. Strategies that enable more selective drug delivery to...

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Main Authors: Victoria Monge-Fuentes, Andréia Biolchi Mayer, Marcos Robalinho Lima, Luiza Ribeiro Geraldes, Larissa Nepomuceno Zanotto, Karla Graziella Moreira, Olimpia Paschoal Martins, Henrique Luís Piva, Maria Sueli Soares Felipe, Andre Correa Amaral, Anamélia Lorenzetti Bocca, Antonio Claudio Tedesco, Márcia Renata Mortari
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/878f8f5c6a6f4583aee909721c20dc25
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https://doaj.org/article/878f8f5c6a6f4583aee909721c20dc25

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