Connecting genetic risk to disease end points through the human blood plasma proteome

Individual genetic variation can affect the levels of protein in blood, but detailed data sets linking these two types of data are rare. Here, the authors carry out a genome-wide association study of levels of over a thousand different proteins, and describe many new SNP-protein interactions.

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Autores principales:	Karsten Suhre, Matthias Arnold, Aditya Mukund Bhagwat, Richard J. Cotton, Rudolf Engelke, Johannes Raffler, Hina Sarwath, Gaurav Thareja, Annika Wahl, Robert Kirk DeLisle, Larry Gold, Marija Pezer, Gordan Lauc, Mohammed A. El-Din Selim, Dennis O. Mook-Kanamori, Eman K. Al-Dous, Yasmin A. Mohamoud, Joel Malek, Konstantin Strauch, Harald Grallert, Annette Peters, Gabi Kastenmüller, Christian Gieger, Johannes Graumann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8795d9d74e404676970c345596c0741f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:8795d9d74e404676970c345596c0741f2021-12-02T14:41:09ZConnecting genetic risk to disease end points through the human blood plasma proteome10.1038/ncomms143572041-1723https://doaj.org/article/8795d9d74e404676970c345596c0741f2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14357https://doaj.org/toc/2041-1723Individual genetic variation can affect the levels of protein in blood, but detailed data sets linking these two types of data are rare. Here, the authors carry out a genome-wide association study of levels of over a thousand different proteins, and describe many new SNP-protein interactions.Karsten SuhreMatthias ArnoldAditya Mukund BhagwatRichard J. CottonRudolf EngelkeJohannes RafflerHina SarwathGaurav TharejaAnnika WahlRobert Kirk DeLisleLarry GoldMarija PezerGordan LaucMohammed A. El-Din SelimDennis O. Mook-KanamoriEman K. Al-DousYasmin A. MohamoudJoel MalekKonstantin StrauchHarald GrallertAnnette PetersGabi KastenmüllerChristian GiegerJohannes GraumannNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Karsten Suhre Matthias Arnold Aditya Mukund Bhagwat Richard J. Cotton Rudolf Engelke Johannes Raffler Hina Sarwath Gaurav Thareja Annika Wahl Robert Kirk DeLisle Larry Gold Marija Pezer Gordan Lauc Mohammed A. El-Din Selim Dennis O. Mook-Kanamori Eman K. Al-Dous Yasmin A. Mohamoud Joel Malek Konstantin Strauch Harald Grallert Annette Peters Gabi Kastenmüller Christian Gieger Johannes Graumann Connecting genetic risk to disease end points through the human blood plasma proteome
description	Individual genetic variation can affect the levels of protein in blood, but detailed data sets linking these two types of data are rare. Here, the authors carry out a genome-wide association study of levels of over a thousand different proteins, and describe many new SNP-protein interactions.
format	article
author	Karsten Suhre Matthias Arnold Aditya Mukund Bhagwat Richard J. Cotton Rudolf Engelke Johannes Raffler Hina Sarwath Gaurav Thareja Annika Wahl Robert Kirk DeLisle Larry Gold Marija Pezer Gordan Lauc Mohammed A. El-Din Selim Dennis O. Mook-Kanamori Eman K. Al-Dous Yasmin A. Mohamoud Joel Malek Konstantin Strauch Harald Grallert Annette Peters Gabi Kastenmüller Christian Gieger Johannes Graumann
author_facet	Karsten Suhre Matthias Arnold Aditya Mukund Bhagwat Richard J. Cotton Rudolf Engelke Johannes Raffler Hina Sarwath Gaurav Thareja Annika Wahl Robert Kirk DeLisle Larry Gold Marija Pezer Gordan Lauc Mohammed A. El-Din Selim Dennis O. Mook-Kanamori Eman K. Al-Dous Yasmin A. Mohamoud Joel Malek Konstantin Strauch Harald Grallert Annette Peters Gabi Kastenmüller Christian Gieger Johannes Graumann
author_sort	Karsten Suhre
title	Connecting genetic risk to disease end points through the human blood plasma proteome
title_short	Connecting genetic risk to disease end points through the human blood plasma proteome
title_full	Connecting genetic risk to disease end points through the human blood plasma proteome
title_fullStr	Connecting genetic risk to disease end points through the human blood plasma proteome
title_full_unstemmed	Connecting genetic risk to disease end points through the human blood plasma proteome
title_sort	connecting genetic risk to disease end points through the human blood plasma proteome
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8795d9d74e404676970c345596c0741f
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Connecting genetic risk to disease end points through the human blood plasma proteome

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