A B-cell developmental gene regulatory network is activated in infant AML.

A B-cell developmental gene regulatory network is activated in infant AML.

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Infant Acute Myeloid Leukemia (AML) is a poorly-addressed, heterogeneous malignancy distinguished by surprisingly few mutations per patient but accompanied by myriad age-specific translocations. These characteristics make treatment of infant AML challenging. While infant AML is a relatively rare dis...

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Autores principales: Hamid Bolouri, Rhonda Ries, Laura Pardo, Tiffany Hylkema, Wanding Zhou, Jenny L Smith, Amanda Leonti, Michael Loken, Jason E Farrar, Timothy J Triche, Soheil Meshinchi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/8799310bde8644c6a5f0b382c4579554
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