Mitochondrial TCA cycle metabolites control physiology and disease
Mitochondrial metabolites contribute to more than biosynthesis, and it is clear that they influence multiple cellular functions in a variety of ways. Here, Martínez-Reyes and Chandel review key metabolites and describe their effects on processes involved in physiology and disease including chromatin...
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Nature Portfolio
2020
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oai:doaj.org-article:87a07826baca4f58b0ed5611da54ac012021-12-02T17:31:54ZMitochondrial TCA cycle metabolites control physiology and disease10.1038/s41467-019-13668-32041-1723https://doaj.org/article/87a07826baca4f58b0ed5611da54ac012020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13668-3https://doaj.org/toc/2041-1723Mitochondrial metabolites contribute to more than biosynthesis, and it is clear that they influence multiple cellular functions in a variety of ways. Here, Martínez-Reyes and Chandel review key metabolites and describe their effects on processes involved in physiology and disease including chromatin dynamics, immunity, and hypoxia.Inmaculada Martínez-ReyesNavdeep S. ChandelNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Inmaculada Martínez-Reyes Navdeep S. Chandel Mitochondrial TCA cycle metabolites control physiology and disease |
description |
Mitochondrial metabolites contribute to more than biosynthesis, and it is clear that they influence multiple cellular functions in a variety of ways. Here, Martínez-Reyes and Chandel review key metabolites and describe their effects on processes involved in physiology and disease including chromatin dynamics, immunity, and hypoxia. |
format |
article |
author |
Inmaculada Martínez-Reyes Navdeep S. Chandel |
author_facet |
Inmaculada Martínez-Reyes Navdeep S. Chandel |
author_sort |
Inmaculada Martínez-Reyes |
title |
Mitochondrial TCA cycle metabolites control physiology and disease |
title_short |
Mitochondrial TCA cycle metabolites control physiology and disease |
title_full |
Mitochondrial TCA cycle metabolites control physiology and disease |
title_fullStr |
Mitochondrial TCA cycle metabolites control physiology and disease |
title_full_unstemmed |
Mitochondrial TCA cycle metabolites control physiology and disease |
title_sort |
mitochondrial tca cycle metabolites control physiology and disease |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/87a07826baca4f58b0ed5611da54ac01 |
work_keys_str_mv |
AT inmaculadamartinezreyes mitochondrialtcacyclemetabolitescontrolphysiologyanddisease AT navdeepschandel mitochondrialtcacyclemetabolitescontrolphysiologyanddisease |
_version_ |
1718380439959240704 |