Mitochondrial TCA cycle metabolites control physiology and disease

Mitochondrial metabolites contribute to more than biosynthesis, and it is clear that they influence multiple cellular functions in a variety of ways. Here, Martínez-Reyes and Chandel review key metabolites and describe their effects on processes involved in physiology and disease including chromatin...

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Autores principales: Inmaculada Martínez-Reyes, Navdeep S. Chandel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/87a07826baca4f58b0ed5611da54ac01
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spelling oai:doaj.org-article:87a07826baca4f58b0ed5611da54ac012021-12-02T17:31:54ZMitochondrial TCA cycle metabolites control physiology and disease10.1038/s41467-019-13668-32041-1723https://doaj.org/article/87a07826baca4f58b0ed5611da54ac012020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13668-3https://doaj.org/toc/2041-1723Mitochondrial metabolites contribute to more than biosynthesis, and it is clear that they influence multiple cellular functions in a variety of ways. Here, Martínez-Reyes and Chandel review key metabolites and describe their effects on processes involved in physiology and disease including chromatin dynamics, immunity, and hypoxia.Inmaculada Martínez-ReyesNavdeep S. ChandelNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Inmaculada Martínez-Reyes
Navdeep S. Chandel
Mitochondrial TCA cycle metabolites control physiology and disease
description Mitochondrial metabolites contribute to more than biosynthesis, and it is clear that they influence multiple cellular functions in a variety of ways. Here, Martínez-Reyes and Chandel review key metabolites and describe their effects on processes involved in physiology and disease including chromatin dynamics, immunity, and hypoxia.
format article
author Inmaculada Martínez-Reyes
Navdeep S. Chandel
author_facet Inmaculada Martínez-Reyes
Navdeep S. Chandel
author_sort Inmaculada Martínez-Reyes
title Mitochondrial TCA cycle metabolites control physiology and disease
title_short Mitochondrial TCA cycle metabolites control physiology and disease
title_full Mitochondrial TCA cycle metabolites control physiology and disease
title_fullStr Mitochondrial TCA cycle metabolites control physiology and disease
title_full_unstemmed Mitochondrial TCA cycle metabolites control physiology and disease
title_sort mitochondrial tca cycle metabolites control physiology and disease
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/87a07826baca4f58b0ed5611da54ac01
work_keys_str_mv AT inmaculadamartinezreyes mitochondrialtcacyclemetabolitescontrolphysiologyanddisease
AT navdeepschandel mitochondrialtcacyclemetabolitescontrolphysiologyanddisease
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